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1例S-1/吉西他滨化疗联合手术切除治疗晚期伴腹膜播散胰腺癌的有效病例

[A case of effective treatment with S-1/gemcitabine chemotherapy and resection for advanced pancreatic cancer with peritoneal dissemination].

作者信息

Koga Hiroki, Miyoshi Atsushi, Nakamura Jun, Ide Takao, Kitahara Kenji, Noshiro Hirokazu

机构信息

Dept. of Surgery, Saga Medical School Faculty of Medicine, Saga University.

出版信息

Gan To Kagaku Ryoho. 2014 May;41(5):665-8.

PMID:24917019
Abstract

A 69-year-old man was admitted to our hospital for abdominal pain. An abdominal computed tomography(CT)scan revealed pancreatictail cancer with peritoneal dissemination. We administered systemic chemotherapy consisting of S-1 and gemcitabine. After 10 courses, the peritoneal dissemination had disappeared and tumor marker levels returned to almost normal values. Thus, we considered the patient to have an effective response, so we performed a distalpancreatectomy and partial resection of the stomach, transverse colon, and left adrenal gland. Eleven months after the operation, the patient is alive with no recurrence.

摘要

一名69岁男性因腹痛入院。腹部计算机断层扫描(CT)显示胰尾癌伴腹膜播散。我们给予了由S-1和吉西他滨组成的全身化疗。10个疗程后,腹膜播散消失,肿瘤标志物水平恢复至几乎正常。因此,我们认为患者有有效反应,于是进行了胰体尾切除术以及胃、横结肠和左肾上腺部分切除术。术后11个月,患者存活且无复发。

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引用本文的文献

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Conversion Therapy for Advanced Pancreatic Cancer: The Case Series and Literature Review.晚期胰腺癌的转化治疗:病例系列与文献综述
Front Pharmacol. 2020 Oct 6;11:579239. doi: 10.3389/fphar.2020.579239. eCollection 2020.