El Zawahry Bakr, Zaki Naglaa, Hafez Vanessa, Abdel Hay Rania, Fahim Aya
Dermatology Department, Cairo University, Giza, Egypt.
Lasers Med Sci. 2014 Nov;29(6):1937-42. doi: 10.1007/s10103-014-1610-8. Epub 2014 Jun 12.
Facial freckles are a cosmetic concern to Egyptians, particularly young females. Several therapeutic lines exist with variable response rates and limitations. Fractional carbon dioxide (FCO2) laser provides minimal ablation and therefore less down time and less side effects. The efficacy and safety of this laser technology have still not been studied in freckles. The aim of this study is to assess the efficacy and safety of FCO2 laser in the treatment of unwanted facial freckles in Egyptians. Twenty patients undergone a single session of FCO2 laser and then were followed up clinically a month later. Photographs were taken before treatment and at follow-up visit and were assessed by three blinded investigators. Percent of global improvement was measured on a 4-point grading scale. Patient's satisfaction and adverse events were recorded. Two patients (10 %) showed grade 1 improvement, while eight patients (40 %) showed grade 2 improvement. Nine patients (45 %) showed grade 3 improvement, and only one patient (5 %) showed grade 4 improvement. FCO2 laser resurfacing is effective and safe in treatment of facial freckles in skin phototypes II-IV. It can offer a more practical alternative to topical treatments, and a cheaper alternative to Q-switched lasers.
面部雀斑是埃及人，尤其是年轻女性关注的美容问题。目前有几种治疗方法，但其有效率和局限性各不相同。二氧化碳点阵激光（FCO2）造成的皮肤剥脱极少，因此停工期较短，副作用也较少。目前尚未对这种激光技术治疗雀斑的疗效和安全性进行研究。本研究的目的是评估FCO2激光治疗埃及人面部多余雀斑的疗效和安全性。20名患者接受了单次FCO2激光治疗，然后在一个月后进行临床随访。在治疗前和随访时拍摄照片，并由三名不知情的研究人员进行评估。整体改善百分比采用4分制评分。记录患者的满意度和不良事件。两名患者（10%）显示1级改善，八名患者（40%）显示2级改善。九名患者（45%）显示3级改善，只有一名患者（5%）显示4级改善。FCO2激光换肤术治疗II-IV型皮肤的面部雀斑有效且安全。它可以为局部治疗提供更实用的替代方案，为调Q激光提供更便宜的替代方案。
