对亚洲皮肤使用四种不同色素激光治疗雀斑和雀斑样痣的回顾性分析。
A retrospective analysis of the management of freckles and lentigines using four different pigment lasers on Asian skin.
作者信息
Ho S G Y, Chan N P Y, Yeung C K, Shek S Y, Kono T, Chan H H L
机构信息
Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.
出版信息
J Cosmet Laser Ther. 2012 Apr;14(2):74-80. doi: 10.3109/14764172.2012.670707.
BACKGROUND
The risk of post-inflammatory hyperpigmentation (PIH) is increased during freckles and lentigines treatment in Asians.
OBJECTIVE
To determine the effectiveness and safety of using 595-nm long pulsed dye laser (LPDL), 755-nm LP Alexandrite laser, 532-nm QS Nd:YAG laser and 532-nm LP potassium-titanyl-phosphate (KTP) laser for the treatment of freckles or lentigines in Asian patients.
METHODS
This is a retrospective study of 40 Chinese patients, who were divided into four groups based on treatment modality using four different pigment lasers. Each patient attended between 1 and 4 treatments (mean of 1.8), at 4-6 weeks intervals, depending on clinical response. Lesional clearance and PIH were assessed by two independent clinicians.
RESULTS
Statistically significant improvement of global and focal facial pigmentation was found after treatment with LPDL, QS Nd:YAG and LP KTP lasers. No significant improvement was found after LP Alexandrite laser. PIH risk was 20% after LP Alexandrite treatment, 10% with QS Nd:YAG, and absent after LPDL and LP KTP treatment.
CONCLUSION
A long pulse laser and small spot size appear to reduce the risks of lentigines treatment in darker skin types.
背景
在亚洲人雀斑和雀斑样痣的治疗过程中，炎症后色素沉着（PIH）的风险会增加。
目的
确定使用595纳米长脉冲染料激光（LPDL）、755纳米长脉冲翠绿宝石激光、532纳米调Q Nd:YAG激光和532纳米长脉冲磷酸钛氧钾（KTP）激光治疗亚洲患者雀斑或雀斑样痣的有效性和安全性。
方法
这是一项对40名中国患者的回顾性研究，根据治疗方式将其分为四组，分别使用四种不同的色素激光。每位患者根据临床反应接受1至4次治疗（平均1.8次），治疗间隔为4至6周。由两名独立的临床医生评估皮损清除情况和PIH。
结果
使用LPDL、调Q Nd:YAG和长脉冲KTP激光治疗后，面部整体和局部色素沉着有统计学意义的改善。长脉冲翠绿宝石激光治疗后未发现明显改善。长脉冲翠绿宝石激光治疗后PIH风险为20%，调Q Nd:YAG为10%，LPDL和长脉冲KTP激光治疗后未出现PIH。
结论
长脉冲激光和小光斑似乎可降低深色皮肤类型雀斑样痣治疗的风险。
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