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前列腺原发性纯小细胞癌非转移病例的化疗完全缓解。

Complete chemotherapeutic regression of a non-metastatic case of primary pure small cell carcinoma of the prostate.

作者信息

Yahyazadeh Seyed H, Abadpour Behrang, Molanaei Saadat, Jamali Arsia

机构信息

Clinical Research Center, Milad General Hospital, Tehran, Iran.

Department of Urology, Milad General Hospital, Tehran, Iran.

出版信息

Curr Urol. 2012 May;6(1):43-5. doi: 10.1159/000338869. Epub 2012 Apr 30.

DOI:10.1159/000338869
PMID:24917709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3783335/
Abstract

Pure small cell carcinoma of the prostate (SCPCa) is a very rare condition usually with poor survival after diagnosis. It seems to show different clinical features compared to other prostate cancer subtypes, specifically adenocarcinoma. Here, we present a 74-year-old man early diagnosed with SCPCa treated with a cisplatine and etoposide regimen. There was no metastasis found in imaging studies and bone scan. The patient mostly complained of obstructive symptoms which were relieved after resection. Interestingly, our patient experienced a disease free condition after chemotherapy and no further progression was found. This could implicate the critical role of early diagnosis in the treatment of SCPCa despite its aggressive nature.

摘要

纯前列腺小细胞癌(SCPCa)是一种非常罕见的疾病,诊断后生存率通常较低。与其他前列腺癌亚型,特别是腺癌相比,它似乎表现出不同的临床特征。在此,我们报告一名74岁的男性,早期诊断为SCPCa,接受了顺铂和依托泊苷方案治疗。影像学检查和骨扫描未发现转移。患者主要抱怨梗阻症状,切除后症状缓解。有趣的是,我们的患者化疗后处于无病状态,未发现进一步进展。这可能意味着尽管SCPCa具有侵袭性,但早期诊断在其治疗中起着关键作用。

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本文引用的文献

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Pure small cell carcinoma of the prostate: a case report and literature review.前列腺纯小细胞癌:一例报告并文献复习
Case Rep Oncol. 2011 Feb 16;4(1):88-95. doi: 10.1159/000324717.
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A case of robot-assisted laparoscopic radical prostatectomy in primary small cell prostate cancer.原发性小细胞前列腺癌机器人辅助腹腔镜根治性前列腺切除术1例。
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Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases.前列腺小细胞癌:95例的形态学和免疫组织化学研究
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Unusual and underappreciated: small cell carcinoma of the prostate.不常见且未得到充分认识:前列腺小细胞癌。
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Small cell carcinoma of the prostate: an immunohistochemical study.前列腺小细胞癌:一项免疫组织化学研究。
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