Capizzello Antonio, Peponi Evangelia, Simou Nafsika, Ntaskagiannis Dimitrios, Tasiou Ifigenia, Kamina Sevasti, Tsekeris Periklis
Radiation Therapy Department, University Hospital of Ioannina, Ioannina, Greece.
Case Rep Oncol. 2011 Feb 16;4(1):88-95. doi: 10.1159/000324717.
Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.
原发性前列腺小细胞癌（SCPCa）是一种罕见的病理实体，具有独特的临床特征且预后较差。我们报告一例经联合放化疗方法治疗的纯SCPCa患者。病理检查结果显示，肿瘤细胞对全细胞角蛋白、突触素、甲状腺转录因子-1和CD56呈阳性反应。前列腺特异性抗原免疫染色为阴性，而血清前列腺特异性抗原在正常范围内。我们回顾现有文献以获取有关纯SCPCa诊断、治疗和预后的更多信息。
