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AngioVac系统在根治性肾切除术联合下腔静脉血栓切除术期间预防肺栓塞的新应用

Novel Use of AngioVac System to Prevent Pulmonary Embolism during Radical Nephrectomy with Inferior Vena Cava Thrombectomy.

作者信息

Brown Robert J, Uhlman Matthew A, Fernandez Joss D, Collins Thomas, Brown James A

机构信息

Department of Urology, University of Iowa, Iowa City, Iowa, USA.

Department of Cardiothoracic Surgery, University of Iowa, Iowa City, Iowa, USA.

出版信息

Curr Urol. 2013 Aug;7(1):34-6. doi: 10.1159/000343550. Epub 2013 Jul 28.

DOI:10.1159/000343550
PMID:24917754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3783293/
Abstract

Venous tumor thrombus occurs in 5-10% of patients with renal cell carcinoma. Surgical excision offers the best chance for survival, but is technically difficult. Risk of pulmonary embolism from venous thrombus or tumor thrombus is high, especially with tumors located higher in the inferior vena cava. Cardiopulmonary bypass may be used when a tumor extends above the diaphragm, but carries significant risk. We present an 86-year-old woman with a 7 cm renal mass extending into the inferior vena cava just below the confluence of the hepatic vessels. Prior to surgery she was found to have increasing pulmonary embolisms despite appropriate anticoagulation. Intraoperatively, the AngioVac aspiration system was utilized to prevent further pulmonary embolism. This is the first reported case of the use of this system during radical nephrectomy.

摘要

静脉肿瘤血栓见于5%至10%的肾细胞癌患者。手术切除提供了最佳的生存机会,但技术上难度较大。静脉血栓或肿瘤血栓导致肺栓塞的风险很高,尤其是肿瘤位于下腔静脉较高位置时。当肿瘤延伸至膈肌上方时可使用体外循环,但风险很大。我们报告一例86岁女性,其7厘米的肾肿物延伸至肝血管汇合处下方的下腔静脉。术前发现尽管进行了适当的抗凝治疗,但她的肺栓塞仍在增加。术中使用了AngioVac抽吸系统以预防进一步的肺栓塞。这是首例在根治性肾切除术中使用该系统的报道病例。

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本文引用的文献

1
Percutaneous extraction of right atrial mass using the Angiovac aspiration system.使用Angiovac抽吸系统经皮提取右心房肿块
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The perioperative management of an inferior vena caval tumor thrombus in patients with renal cell carcinoma.肾细胞癌患者下腔静脉肿瘤血栓的围手术期处理。
Urol Oncol. 2013 Jul;31(5):517-21. doi: 10.1016/j.urolonc.2011.03.006. Epub 2011 Apr 21.
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Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension.2009 UICC/AJCC TNM 分期系统对伴有静脉侵犯的肾细胞癌的预后影响。
Eur Urol. 2011 Jan;59(1):120-7. doi: 10.1016/j.eururo.2010.10.001. Epub 2010 Oct 13.
4
Resection of renal tumors invading the vena cava.侵犯腔静脉的肾肿瘤切除术。
Urol Clin North Am. 2008 Nov;35(4):657-71; viii. doi: 10.1016/j.ucl.2008.07.013.
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Results of endoluminal occlusion of the inferior vena cava during radical nephrectomy and thrombectomy.根治性肾切除术及血栓切除术期间下腔静脉腔内闭塞的结果。
Eur Urol. 2008 Oct;54(4):778-83. doi: 10.1016/j.eururo.2008.05.016. Epub 2008 May 27.
6
Surgery insight: management of renal cell carcinoma with associated inferior vena cava thrombus.手术洞察:伴有下腔静脉血栓的肾细胞癌的管理
Nat Clin Pract Urol. 2008 Jun;5(6):329-39. doi: 10.1038/ncpuro1122. Epub 2008 May 13.
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Long-term experience with management of renal cell carcinoma involving the inferior vena cava.肾细胞癌侵犯下腔静脉的长期管理经验。
Urology. 2003 Jan;61(1):89-92. doi: 10.1016/s0090-4295(02)02119-2.
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Management of renal cell carcinoma with level III thrombus in the inferior vena cava.伴有下腔静脉Ⅲ级血栓的肾细胞癌的治疗
J Urol. 2002 Oct;168(4 Pt 1):1374-7. doi: 10.1016/S0022-5347(05)64452-7.