Kim Yong Jin, Park Chan Woo, Ku Seung-Yup
Department of Obstetrics and Gynecology, Guro Hospital, Korea University, Seoul, Korea.
Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University, College of Medicine, Seoul, Korea.
Semin Reprod Med. 2014 Jul;32(4):306-12. doi: 10.1055/s-0034-1375183. Epub 2014 Jun 11.
Intrauterine insemination (IUI) is a widely used fertility treatment for couples with male and/or non-male factor infertility and is a relatively simple and inexpensive procedure. When used for unexplained infertility, IUI combined with ovarian stimulation increases the pregnancy rates, but evidence does not support this to be true when applied for male factor infertility. Recently, the revised World Health Organization laboratory manual for semen criteria provided a new insight for practical guidelines. Further randomized, controlled studies are necessary to develop standardized IUI strategies. The authors reviewed, via literature search, on the indications, prognostic factors, ovarian stimulation protocols, and methods that have been employed for IUI treatment.
宫腔内人工授精（IUI）是一种广泛应用于男性和/或非男性因素不孕夫妇的生育治疗方法，是一种相对简单且成本较低的程序。当用于不明原因不孕时，IUI联合卵巢刺激可提高妊娠率，但证据并不支持其应用于男性因素不孕时也同样如此。最近，世界卫生组织修订的精液标准实验室手册为实用指南提供了新的见解。有必要进行进一步的随机对照研究以制定标准化的IUI策略。作者通过文献检索，对IUI治疗的适应证、预后因素、卵巢刺激方案及所采用的方法进行了综述。
