Zivelonghi Carlo, Ghione Matteo, Kilickesmez Kadriye, Loureiro Rodrigo Estevez, Foin Nicolas, Lindsay Alistair, de Silva Ranil, Ribichini Flavio, Vassanelli Corrado, Di Mario Carlo
aCardiovascular Biomedical Research Unit, Royal Brompton Hospital bImperial College, London, UK cDepartment of Medicine, University of Verona, Verona, Italy.
J Cardiovasc Med (Hagerstown). 2014 Jul;15(7):543-53. doi: 10.2459/JCM.0000000000000032.
Optical coherence tomography (OCT) is a light-based technology that provides very high spatial resolution images. OCT has been initially employed as a research tool to investigate plaque morphology and stent strut coverage. The introduction of frequency domain OCT allowing fast image acquisition during a prolonged contrast injection via the guiding catheter has made OCT applicable for guidance of coronary interventions. In this manuscript, the various applications of OCT are reviewed, from assessment of plaque vulnerability and severity to characteristics of unstable lesions and thrombus burden to stent optimization and evaluation of late results.
光学相干断层扫描（OCT）是一种基于光的技术，可提供具有非常高空间分辨率的图像。OCT最初被用作研究工具，以研究斑块形态和支架小梁覆盖情况。频域OCT的引入使得在通过引导导管进行长时间造影剂注射期间能够快速采集图像，从而使OCT适用于冠状动脉介入治疗的指导。在本手稿中，将对OCT的各种应用进行综述，从斑块易损性和严重程度的评估到不稳定病变和血栓负荷的特征，再到支架优化和晚期结果评估。
