Dash Debabrata
S.L Raheja (A Fortis Associate) Hospital, Nanavati Superspeciality Hospital, Mumbai, India.
Indian Heart J. 2017 May-Jun;69(3):407-410. doi: 10.1016/j.ihj.2016.12.022. Epub 2017 Jan 22.
Intravascular imaging has improved our understanding of in vivo pathophysiology of coronary artery disease (CAD) and predicted decision-making in percutaneous coronary intervention (PCI). Intravascular ultrasound (IVUS) has emerged as the first clinical imaging method contributing significantly to modern PCI techniques. This modality has outlived many other intravascular techniques 26 years after its inception. It has assisted us in understanding dynamics of atherosclerosis and provides several unique insights into plaque burden, remodeling, and restenosis. It is useful as an imaging endpoint in large progression-regression trial and as workhorse in many catheterization laboratories. IVUS guidance appears to be most beneficial in complex lesion subsets that are being treated with drug-eluting stents. The recent introduction of optical coherence tomography (OCT), a light based imaging technique, has further expanded this field because of its higher resolution and faster image acquisition. The omnipresence of OCT raises the question: Does IVUS have a role in the era of OCT? Whether OCT is superior to IVUS in routine clinical practice? Even if OCT is currently gaining clinical significance in detailed planning of interventional strategies and stent optimization in complex lesion subsets, it is the much younger technique and has to prove its worth. Nevertheless, undoubtedly IVUS plays significant role in studies on coronary atherosclerosis and for guidance of PCI. In fact, both the methods are complementary rather than competitive.
血管内成像增进了我们对冠状动脉疾病(CAD)体内病理生理学的理解,并为经皮冠状动脉介入治疗(PCI)中的决策提供了依据。血管内超声(IVUS)已成为对现代PCI技术有重大贡献的首个临床成像方法。这种技术自问世26年来,比许多其他血管内技术都更具生命力。它帮助我们了解动脉粥样硬化的动态变化,并对斑块负荷、重塑和再狭窄提供了一些独特的见解。它在大型进展-消退试验中作为成像终点很有用,在许多导管实验室中也是主力手段。IVUS引导在使用药物洗脱支架治疗的复杂病变亚组中似乎最有益。最近引入的光学相干断层扫描(OCT),一种基于光的成像技术,因其更高的分辨率和更快的图像采集速度,进一步扩展了这个领域。OCT的广泛应用引发了一个问题:在OCT时代,IVUS还有作用吗?在常规临床实践中,OCT是否优于IVUS?即使OCT目前在复杂病变亚组的介入策略详细规划和支架优化方面正获得临床意义,但它是一项更新的技术,还必须证明其价值。然而,毫无疑问,IVUS在冠状动脉粥样硬化研究和PCI指导中发挥着重要作用。事实上,这两种方法是互补而非竞争的。