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临终关怀机构能预测哪些患者会在六个月内死亡吗?

Can hospices predict which patients will die within six months?

作者信息

Harris Pamela S, Stalam Tapati, Ache Kevin A, Harrold Joan E, Craig Teresa, Teno Joan, Smither Eugenia, Dougherty Meredith, Casarett David

机构信息

1 Kansas City Hospice and Palliative Care , Kansas City, Missouri.

出版信息

J Palliat Med. 2014 Aug;17(8):894-8. doi: 10.1089/jpm.2013.0631. Epub 2014 Jun 12.

Abstract

OBJECTIVE

To determine whether it is possible to predict, at the time of hospice enrollment, which patients will die within 6 months.

DESIGN

Electronic health record-based retrospective cohort study.

SETTING

Patients admitted to 10 hospices in the CHOICE network (Coalition of Hospices Organized to Investigate Comparative Effectiveness).

PARTICIPANTS

Hospice patients.

MAIN OUTCOME MEASURES

Mortality at 6 months following hospice admission.

RESULTS

Among 126,620 patients admitted to 10 hospices, 118,532 (93.6%) died within 6 months. In a multivariable logistic regression model, five characteristics were independent predictors of 6-month mortality. For instance, patients younger than 65 years were less likely to die within 6 months (odds ratio [OR] 0.64; 95% confidence interval [CI] 0.45-0.91; p=0.014). Conversely, male patients were more likely to die within 6 months (OR 1.47; 95% CI 1.05-2.02; p=;0.036). After adjusting for other variables in this model, there were several subgroups with a low probability of 6-month probability (e.g., stroke and Palliative Performance Scale [PPS] score=50; adjusted probability of 6-month mortality=39.4%; 95% CI: 13.9%-72.5%). However, 95% confidence intervals of these 6-month mortality predictions extended above 50%.

CONCLUSIONS

Hospices might use several variables to identify patients with a relatively low risk for 6-month mortality and who therefore may become ineligible to continue hospice services if they fail to show significant disease progression.

摘要

目的

确定在临终关怀登记时能否预测哪些患者会在6个月内死亡。

设计

基于电子健康记录的回顾性队列研究。

地点

CHOICE网络(组织起来调查比较效果的临终关怀联盟)中的10家临终关怀机构收治的患者。

参与者

临终关怀患者。

主要观察指标

临终关怀入院后6个月的死亡率。

结果

在10家临终关怀机构收治的126,620例患者中,118,532例(93.6%)在6个月内死亡。在多变量逻辑回归模型中,五个特征是6个月死亡率的独立预测因素。例如,65岁以下的患者在6个月内死亡的可能性较小(比值比[OR]0.64;95%置信区间[CI]0.45 - 0.91;p = 0.014)。相反,男性患者在6个月内死亡的可能性更大(OR 1.47;95% CI 1.05 - 2.02;p = 0.036)。在该模型中对其他变量进行调整后,有几个亚组6个月死亡概率较低(例如,中风且姑息治疗表现量表[PPS]评分为50;6个月死亡率的调整概率为39.4%;95% CI:13.9% - 72.5%)。然而,这些6个月死亡率预测的95%置信区间超过了50%。

结论

临终关怀机构可以使用几个变量来识别6个月死亡率相对较低的患者,如果这些患者没有出现明显的疾病进展,可能不再符合继续接受临终关怀服务的条件。

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