硝酸甘油使用的最新情况。
Update on nitroglycerin use.
作者信息
Andrien P, Lemberg L
机构信息
Department of Medicine, University of Miami School of Medicine, FL 33101.
出版信息
Heart Lung. 1989 Jan;18(1):100-1.
PMID:2492267
Abstract
Tolerance to nitrates occurs when this class of drugs is administered in a continuous around-the-clock regimen. Nitrate-free intervals from 10 to 12 hours are recommended to prevent nitrate tolerance. Full response with renewed administration occurs with interrupted nitrate therapy.
摘要
当以持续24小时不间断的方案使用这类药物时，会出现对硝酸盐的耐受性。建议设置10至12小时的无硝酸盐间隔期，以预防硝酸盐耐受性。重新给药时，中断硝酸盐治疗可实现完全反应。
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