Papadopoulos M, Edmunds B, Fenerty C, Khaw P T
Glaucoma Service, Moorfields Eye Hospital, London, UK.
Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Eye (Lond). 2014 Aug;28(8):931-43. doi: 10.1038/eye.2014.140. Epub 2014 Jun 13.
Most children with glaucoma will require surgery in their lifetime, often in their childhood years. The surgical management of childhood glaucoma is however challenging, largely because of its greater potential for failure and complications as compared with surgery in adults. The available surgical repertoire for childhood glaucoma has remained relatively unchanged for many years with most progress owing to modifications to existing surgery. Although the surgical approach to childhood glaucoma varies around the world, angle surgery remains the preferred initial surgery for primary congenital glaucoma and a major advance has been the concept of incising the whole of the angle (circumferential trabeculotomy). Simple modifications to the trabeculectomy technique have been shown to considerably minimise complications. Glaucoma drainage devices maintain a vital role for certain types of glaucoma including those refractory to other surgery. Cyclodestruction continues to have a role mainly for patients following failed drainage/filtering surgery. Although the prognosis for childhood glaucoma has improved significantly since the introduction of angle surgery, there is still considerable progress to be made to ensure a sighted lifetime for children with glaucoma all over the world. Collaborative approaches to researching and delivering this care are required, and this paper highlights the need for more high-quality prospective surgical trials in the management of the childhood glaucoma.
大多数青光眼患儿一生中都需要接受手术,且往往是在童年时期。然而,儿童青光眼的手术治疗颇具挑战性,主要原因在于与成人手术相比,其手术失败和出现并发症的可能性更大。多年来,儿童青光眼的可用手术方法相对没有变化,大多数进展是对现有手术进行改良的结果。尽管世界各地治疗儿童青光眼的手术方法有所不同,但对于原发性先天性青光眼,房角手术仍是首选的初始手术,一项重大进展是切开整个房角(环形小梁切开术)的概念。对小梁切除术技术进行简单改良已被证明可大大减少并发症。青光眼引流装置对于某些类型的青光眼,包括对其他手术无效的青光眼,仍起着至关重要的作用。睫状体破坏术主要仍适用于引流/滤过手术失败的患者。尽管自房角手术问世以来,儿童青光眼的预后有了显著改善,但要确保全世界青光眼患儿一生都有视力,仍有相当大的进展空间。需要采取协作方式来研究和提供这种治疗,本文强调在儿童青光眼治疗中需要更多高质量的前瞻性手术试验。