Ozgun Alpaslan, Tuncel Tolga, Emirzeoglu Levent, Haholu Abdullah
Department of Medical Oncology, Gulhane Military Medical Academy Haydarpasa Training Hospital, Istanbul, Turkey.
Department of Pathology, Gulhane Military Medical Academy Haydarpasa Training Hospital, Istanbul, Turkey.
BMJ Case Rep. 2014 Jun 12;2014:bcr2014203791. doi: 10.1136/bcr-2014-203791.
Basal cell adenocarcinoma (BCAC) is a rare tumour of the salivary glands and often associated with a good prognosis. The present case had BCAC of the parotid gland as the second primary tumour in addition to breast cancer. The patient was a 66-year-old woman who underwent mastectomy due to breast cancer. She then underwent adjuvant chemotherapy and adjuvant hormone therapy. After 4 years of disease-free follow-up, the patient presented with a swelling on the left cheek. The examination of the biopsy specimen revealed BCAC of the parotid gland. The patient then underwent left parathyroidectomy plus left neck dissection. Adjuvant radiotherapy was performed. Despite the therapy, the patient developed four local recurrences within 1 year, and then developed metastasis to the pleura. A swelling in the parotid gland in a patient with breast cancer should be carefully screened for the presence of a second primary tumour.
基底细胞腺癌（BCAC）是一种罕见的涎腺肿瘤，通常预后良好。本病例中，腮腺基底细胞腺癌是除乳腺癌外的第二原发性肿瘤。患者为一名66岁女性，因乳腺癌接受了乳房切除术。随后她接受了辅助化疗和辅助激素治疗。在无病随访4年后，患者左侧脸颊出现肿胀。活检标本检查显示为腮腺基底细胞腺癌。患者随后接受了左侧甲状旁腺切除术加左侧颈部清扫术。进行了辅助放疗。尽管进行了治疗，患者在1年内出现了4次局部复发，随后发生了胸膜转移。乳腺癌患者腮腺出现肿胀时，应仔细筛查是否存在第二原发性肿瘤。
