Siegel Matthew, Milligan Briana, Chemelski Bruce, Payne David, Ellsworth Beth, Harmon Jamie, Teer Olivia, Smith Kahsi A
Developmental Disorders Program, Spring Harbor Hospital, 123 Andover Road, Westbrook, ME, 04092, USA,
J Autism Dev Disord. 2014 Dec;44(12):3026-32. doi: 10.1007/s10803-014-2157-z.
Psychiatric hospitalization of children with autism spectrum disorder and/or intellectual disability is common, however, the effectiveness of this intervention is largely unknown. Thirty-eight clinically-referred children 8-19 years old admitted to a specialized inpatient psychiatry unit were assessed by a consistent caregiver on the Aberrant Behavior Checklist-Irritability (ABC-I) subscale at admission, discharge and 2 months post discharge. There was a decrease in the mean ABC-I score from admission (27.3, SD 7.4) to discharge (11.9, SD 8.8), which was sustained at 2 months post discharge (14.8, SD 9.3) (p < 0.001). Seventy-eight percent of the subjects were rated as "Improved" on the clinician Clinical Global Impressions Improvement scale at discharge. The study is limited by lack of a control group, but offers preliminary evidence for specialized inpatient psychiatry as an intervention for serious behavioral disturbance in this population.
患有自闭症谱系障碍和/或智力残疾的儿童接受精神科住院治疗很常见，然而，这种干预措施的有效性在很大程度上尚不清楚。38名年龄在8至19岁、被转介至一家专门的住院精神科病房的儿童，由一名固定的照顾者在入院时、出院时及出院后2个月，根据异常行为检查表-易激惹性（ABC-I）子量表进行评估。ABC-I平均得分从入院时的27.3（标准差7.4）降至出院时的11.9（标准差8.8），并在出院后2个月维持在14.8（标准差9.3）（p < 0.001）。在出院时，78%的受试者在临床医生的临床总体印象改善量表上被评为“改善”。该研究因缺乏对照组而受到限制，但为专门的住院精神科治疗作为该人群严重行为障碍的一种干预措施提供了初步证据。
