Van Heerden J, Bainbridge N, Burroughs R E, Kriek N P
Department of Companion Animal Medicine and Surgery, Faculty of Veterinary Science, Medical University of Southern Africa, Medunsa.
J Wildl Dis. 1989 Jan;25(1):70-5. doi: 10.7589/0090-3558-25.1.70.
Clinical signs of a fatal disease resembling those of canine distemper were observed in two groups of captive wild dog (Lycaon pictus) pups 13 days after vaccination with a commercially available combination vaccine for dogs which contained a live attenuated strain of canine distemper virus. Histopathological examination of tissues revealed the presence of intranuclear inclusion bodies in neurons and lesions resembling canine distemper as well as colonies of an Encephalitozoon sp. in the central nervous system and kidneys. Lesions were observed in both organs which resembled those described in other species infected with Encephalitozoon cuniculi.
在两组圈养的野生犬科动物（非洲野犬）幼崽接种一种市售犬用联合疫苗（其中含有犬瘟热病毒减毒株）13天后，观察到了一种类似犬瘟热的致命疾病的临床症状。组织的组织病理学检查显示，神经元中存在核内包涵体，病变类似于犬瘟热，同时在中枢神经系统和肾脏中发现了一种脑胞内原虫属的菌落。在这两个器官中都观察到了病变，类似于其他感染兔脑胞内原虫的物种中所描述的病变。
