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内皮素-1与丝裂原活化蛋白激酶相关疼痛的纳米物理治疗信号转导综述

A Review of Signal Transduction of Endothelin-1 and Mitogen-activated Protein Kinase-related Pain for Nanophysiotherapy.

作者信息

Lee Lim-Kyu, Kim Ju-Hyun, Kim Mee-Young, Lee Jeong-Uk, Yang Seung-Min, Jeon Hye-Joo, Lee Won-Deok, Noh Ji-Woong, Kwak Taek-Yong, Jang Sung-Ho, Lee Tae-Hyun, Kim Bokyung, Kim Junghwan

机构信息

Laboratory of Health Science and Nanophysiotherapy, Department of Physical Therapy, Graduate School, Yongin University, Republic of Korea.

Department of Taekwondo Instructor Education, Yongin University, Republic of Korea.

出版信息

J Phys Ther Sci. 2014 May;26(5):789-92. doi: 10.1589/jpts.26.789. Epub 2014 May 29.

DOI:10.1589/jpts.26.789
PMID:24926154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4047254/
Abstract

[Purpose] An understanding of pain is very important in the study of nanophysiotherapy. In this review, we summarize the mechanisms of endothelin-1 (ET-1)- and mitogen-activated protein kinase (MAPK)-related pain, and suggest their applications in pain physiotherapy. [Method] This review focuses on the signal transduction of pain and its mechanisms. [Results] Our reviews show that mechanisms of ET-1- and MAPK-related pain exist. [Conclusions] In this review article, we carefully discuss the signal transduction in ET-1- and MAPK-related pain with reference to pain nanophysiotherapy from the perspective of nanoparticle-associated signal transduction.

摘要

[目的] 了解疼痛在纳米物理治疗研究中非常重要。在本综述中，我们总结了内皮素-1（ET-1）和丝裂原活化蛋白激酶（MAPK）相关疼痛的机制，并提出它们在疼痛物理治疗中的应用。[方法] 本综述聚焦于疼痛的信号转导及其机制。[结果] 我们的综述表明存在ET-1和MAPK相关疼痛的机制。[结论] 在这篇综述文章中，我们从纳米颗粒相关信号转导的角度，结合疼痛纳米物理治疗，仔细讨论了ET-1和MAPK相关疼痛中的信号转导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f7/4047254/f2d6494e2a68/jpts-26-789-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f7/4047254/f2d6494e2a68/jpts-26-789-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f7/4047254/f2d6494e2a68/jpts-26-789-g001.jpg

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