Das Anup K
Department of Medicine and I/C Hepatology Clinic, Assam Medical College, Dibrugarh, Assam, India.
J Glob Infect Dis. 2014 Apr;6(2):65-72. doi: 10.4103/0974-777X.132042.
Ascariasis mainly contributes to the global helminthic burden by infesting a large number of children in the tropical countries. Hepato-biliary ascariasis (HBA) is becoming a common entity now than in the past owing to the frequent usage of ultrasonograms and endoscopic diagnostic procedures in the clinical practice. There are a variety of manifestations in HBA and diagnosis depends on a high index of suspicion in endemic areas coupled with subsequent confirmation by sonographic or endoscopic demonstration of the worm. Most of them present with acute abdomen and jaundice. Oriental or recurrent pyogenic cholangiopathy is possibly the result of HBA, commonly encountered in South-East Asian countries. Conservative treatment with anthelminthic agents is used in the majority. Failure to respond to medical therapy usually indicates the need for endoscopic or surgical interventions. Overall, mortality is low and prognosis is good, but many epidemiological and immunological aspects of Ascaris infection are unclear, meaning our understanding the disease and infection still remains incomplete. Therefore, it is difficult to definitely put down a fixed modality of treatment for HBA. This underscores the need for further studies as ascariasis has the potential to adversely affect the national socio-economy by compromising the health of children and adults alike with its sheer number.
蛔虫病主要通过感染热带国家的大量儿童,加重了全球的蠕虫负担。与过去相比,由于临床实践中超声检查和内镜诊断程序的频繁使用,肝-胆蛔虫病(HBA)现在已成为一种常见疾病。HBA有多种表现,诊断取决于流行地区的高度怀疑指数,随后通过超声或内镜显示蠕虫来确诊。大多数患者表现为急腹症和黄疸。东方型或复发性化脓性胆管炎可能是HBA的结果,在东南亚国家很常见。大多数情况下采用驱虫剂进行保守治疗。药物治疗无效通常表明需要进行内镜或手术干预。总体而言,死亡率低,预后良好,但蛔虫感染的许多流行病学和免疫学方面尚不清楚,这意味着我们对该疾病和感染的理解仍然不完整。因此,很难确定HBA的固定治疗方式。这突出了进一步研究的必要性,因为蛔虫病有可能通过影响儿童和成人的健康,以其庞大的数量对国家社会经济产生不利影响。