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静脉注射免疫球蛋白治疗重症艰难梭菌结肠炎

Intravenous immunoglobulin in the treatment of severe clostridium difficile colitis.

作者信息

Shah Nihar, Shaaban Hamid, Spira Robert, Slim Jihad, Boghossian Jack

机构信息

Department of Gastroenterology, Saint Michael's Medical Center, School of Health and Medical Sciences, Seton Hall University, New Jersey, USA.

Department of Infectious Diseases, Saint Michael's Medical Center, School of Health and Medical Sciences, Seton Hall University, New Jersey, USA.

出版信息

J Glob Infect Dis. 2014 Apr;6(2):82-5. doi: 10.4103/0974-777X.132053.

DOI:10.4103/0974-777X.132053
PMID:24926170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4049046/
Abstract

Intravenous immunoglobulin (IVIG) has been utilized in patients with recurrent and refractory Clostridium difficile colitis. It is increasingly being used in patients with initial clinical presentation of severe colitis. Herein, we report a case of severe C. Difficile colitis successfully treated with IVIG with a review of the medical literature to identify the optimal timing and clinical characteristics for this treatment strategy.

摘要

静脉注射免疫球蛋白(IVIG)已被用于治疗复发性和难治性艰难梭菌结肠炎患者。它越来越多地用于初发临床表现为重症结肠炎的患者。在此,我们报告一例通过IVIG成功治疗的重症艰难梭菌结肠炎病例,并回顾医学文献以确定该治疗策略的最佳时机和临床特征。

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NDT Plus. 2008 Feb;1(1):20-22. doi: 10.1093/ndtplus/sfm008. Epub 2007 Dec 19.
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Clostridium difficile infection: new insights into management.艰难梭菌感染:管理的新见解。
Mayo Clin Proc. 2012 Nov;87(11):1106-17. doi: 10.1016/j.mayocp.2012.07.016.
3
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4
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Am J Geriatr Pharmacother. 2007 Mar;5(1):48-51. doi: 10.1016/j.amjopharm.2007.03.001.
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