Wu Zhaohui, Zhao Quanjun, Tian Zengmin, Zhang Jianning, Xiao Xia, Lin Hong, Wang Hong, Wang Fuli
Department of Neurosurgery, Navy General Hospital of People's Liberation Army, Beijing 100048, P.R. China.
Exp Ther Med. 2014 Jun;7(6):1728-1732. doi: 10.3892/etm.2014.1620. Epub 2014 Mar 12.
The aim of the present study was to evaluate the efficacy and safety of a newly developed robot-assisted frameless stereotactic system for deep electrode implantation and radiofrequency thermocoagulation (RFTC). Deep-electrode implantation was performed in the bilateral mesial temporal lobes of seven patients. Following the implantation of the deep electrodes through the monitored designed path, the epileptogenic zones were determined with the assistance of a robot system. Deep electrode electroencephalograms were recorded prior to and following RFTC. Treatment outcomes were evaluated by computed tomography scans and Engel classification criteria. The procedure was well tolerated by all patients with no patients suffered from severe permanent complications. After follow-ups for 34-62 months, four patients achieved Engel class I, including three patients with Ia classification, two patients were classified as Engel class IVa and one patient was classified as Engel class IVc. Therefore, robot-assisted frameless stereotaxy for deep electrode implantation and RFTC is indicated to be a safe and effective method that may be used effectively in clinical practice.
本研究的目的是评估一种新开发的机器人辅助无框架立体定向系统用于深部电极植入和射频热凝（RFTC）的有效性和安全性。在7例患者的双侧颞叶内侧进行了深部电极植入。通过监测设计路径植入深部电极后，在机器人系统的辅助下确定致痫区。在RFTC前后记录深部电极脑电图。通过计算机断层扫描和Engel分类标准评估治疗结果。所有患者对该操作耐受性良好，无患者出现严重永久性并发症。随访34 - 62个月后，4例患者达到Engel I级，其中3例为Ia级，2例为Engel IVa级，1例为Engel IVc级。因此，机器人辅助无框架立体定向技术用于深部电极植入和RFTC被证明是一种安全有效的方法，可有效应用于临床实践。
