Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA.
Chem Soc Rev. 2015 Jan 21;44(2):500-14. doi: 10.1039/c4cs00140k.
In this review, we describe the construction of gated molecular baskets, discuss their mechanism of action in regulating the exchange of guests and illustrate the potential of these concave hosts to act as catalysts for controlling chemical reactions. Importantly, a number of computational and experimental studies have suggested that gated baskets ought to unfold their gates at the rim for permitting the passage of guests to/from their inner space. These dynamic hosts are therefore offered as useful models for investigating the process of gating in artificial systems. Furthermore, gated baskets should permit examining the benefit of controlling the rate by which reactants access a gated catalyst for promoting chemical reactions occurring in its confined space.
在这篇综述中，我们描述了门控分子篮的构建，讨论了它们在调节客体交换方面的作用机制，并说明了这些凹形主体作为控制化学反应的催化剂的潜力。重要的是，一些计算和实验研究表明，门控篮应该在边缘展开它们的门，以允许客体进出它们的内部空间。这些动态主体因此被作为研究人工系统中门控过程的有用模型。此外，门控篮应该允许检查控制反应物进入门控催化剂的速度来促进其受限空间内发生的化学反应的益处。
