Qiao Na-Na, Sun Ruo-Peng
Department of Pediatrics, Qilu Hospital, Shandong University, Jinan 250012, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2014 Jun;16(6):567-70.
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a type of newly recognized autoimmune encephalitis which is commonly seen in children, but its precise etiology is still uncertain. To reveal the etiology of anti-NMDAR encephalitis is very necessary for understanding its pathology, and for starting immune-related therapy as early as possible to improve its prognosis. In the initial literature, tumor, especially teratoma is more related with the anti-NMDAR encephalitis. In recent research, its etiology is related to infection and heredity. This article reviews the recognition and variation of the etiology of anti-NMDAR encephalitis.
抗N-甲基-D-天冬氨酸受体（NMDAR）脑炎是一种新发现的自身免疫性脑炎，常见于儿童，但其确切病因仍不明确。揭示抗NMDAR脑炎的病因对于了解其病理以及尽早开展免疫相关治疗以改善预后非常必要。在最初的文献中，肿瘤，尤其是畸胎瘤与抗NMDAR脑炎的关系更为密切。在最近的研究中，其病因与感染和遗传有关。本文综述了抗NMDAR脑炎病因的认识及变化。
