与利培酮治疗相关的阴茎异常勃起。

Priapism associated with risperidone treatment.

机构信息

Abarbanel Mental Health Center, Tel Aviv University, Israel.

出版信息

Int J Psychiatry Clin Pract. 2000;4(3):237-9. doi: 10.1080/13651500050518145.

Abstract

Priapism is the occurrence of sustained and painful erection that does not result from sexual desire and fails to subside despite orgasm. It is often accompanied by pain and tenderness. The aetiologies are idiopathic, alcohol abuse, drug therapy, perinatal trauma and sickle-cell anaemia. It is a very rare adverse effect of psychotropic medications, due to alphaadrenergic receptor blockade. Priapism is reported in a 19-year-old physically healthy mental patient after 4 days of risperidone treatment 2 mg/day. ( Int J Psych Clin Pract 2000; 4: 237 - 239).

摘要

阴茎异常勃起是指在没有性欲的情况下发生的持续且疼痛的勃起，并且在射精后也不会消退。它通常伴随着疼痛和压痛。其病因包括特发性、酒精滥用、药物治疗、围产期创伤和镰状细胞性贫血。它是一种非常罕见的精神药物的不良反应，是由于α肾上腺素能受体阻断引起的。在一名 19 岁的身体健康的精神病人接受利培酮治疗 4 天后，每天 2 毫克，报告出现了阴茎异常勃起。（国际精神病临床实践杂志 2000；4: 237-239）。