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产前肾积水:产后评估与管理

Prenatal hydronephrosis: postnatal evaluation and management.

作者信息

Vemulakonda Vijaya, Yiee Jenny, Wilcox Duncan T

机构信息

Department of Pediatric Urology, Children's Hospital Colorado, 13123 East 16th Avenue, Campus Box B-463, Aurora, CO, 80045, USA,

出版信息

Curr Urol Rep. 2014 Aug;15(8):430. doi: 10.1007/s11934-014-0430-5.

DOI:10.1007/s11934-014-0430-5
PMID:24927968
Abstract

Congenital hydronephrosis is one of the most common anomalies identified on antenatal ultrasound. The underlying etiology of congenital hydronephrosis is multifold, ranging from transient hydronephrosis in utero to clinically significant congenital anomalies of the kidney and urinary tract. While traditional management of hydronephrosis was aimed at relieving symptoms, the advent of routine prenatal ultrasound has led to a shift in the goal of treatment to prevention of renal injury in the asymptomatic patient. However, despite this focus on renal preservation, the diagnostic criteria for identification of children "at risk" for renal damage that can be alleviated by surgical treatment remain a subject of debate. Both antenatal and postnatal imaging studies have been evaluated as indicators for potential reversible renal damage and have been used as potential indicators of the need for surgical intervention. The aim of this review is to discuss the current literature regarding the role of postnatal clinical and radiographic evaluation to identify children who may benefit from early surgical intervention.

摘要

先天性肾积水是产前超声检查中最常见的异常情况之一。先天性肾积水的潜在病因是多方面的,从子宫内的短暂性肾积水到具有临床意义的肾脏和泌尿系统先天性异常。虽然传统的肾积水治疗旨在缓解症状,但常规产前超声的出现导致治疗目标转向对无症状患者预防肾损伤。然而,尽管重点在于肾脏保护,但用于识别可通过手术治疗缓解肾损伤 “风险” 儿童的诊断标准仍是一个有争议的话题。产前和产后影像学检查均已作为潜在可逆性肾损伤的指标进行评估,并已被用作手术干预必要性的潜在指标。本综述的目的是讨论当前关于产后临床和影像学评估在识别可能从早期手术干预中获益儿童方面作用的文献。

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1
Prenatal hydronephrosis: postnatal evaluation and management.产前肾积水:产后评估与管理
Curr Urol Rep. 2014 Aug;15(8):430. doi: 10.1007/s11934-014-0430-5.
2
[Postnatal follow-up of children having antenatal hydronephrosis].[产前肾积水患儿的产后随访]
Med Pregl. 2008 Nov-Dec;61(11-12):596-600. doi: 10.2298/mpns0812596m.
3
Current management of antenatal hydronephrosis.产前肾积水的当前处理方法。
Pediatr Nephrol. 2013 Feb;28(2):237-43. doi: 10.1007/s00467-012-2240-7. Epub 2012 Jul 27.
4
Postnatal evaluation and outcome of infants with antenatal hydronephrosis.产前肾积水婴儿的产后评估及预后
Acta Clin Croat. 2011 Dec;50(4):451-5.
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Antenatal hydronephrosis: negative predictive value of normal postnatal ultrasound--a 5-year study.产前肾积水:产后超声检查正常的阴性预测值——一项为期5年的研究
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Am J Perinatol. 2011 Sep;28(8):613-8. doi: 10.1055/s-0031-1276735. Epub 2011 Apr 14.
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A New Grading System for the Management of Antenatal Hydronephrosis.一种用于产前肾积水管理的新分级系统。
Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1783-90. doi: 10.2215/CJN.12861214. Epub 2015 Jul 31.

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Renal cortical transit time in the evaluation of prenatally detected presumed pelvi ureteric junction like obstruction: A systematic review.肾皮质通过时间在产前检测疑似肾盂输尿管连接部梗阻评估中的应用:一项系统评价
Indian J Urol. 2021 Apr-Jun;37(2):116-124. doi: 10.4103/iju.IJU_236_20. Epub 2021 Apr 1.
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本文引用的文献

1
Variability in use of voiding cystourethrogram during initial evaluation of infants with congenital hydronephrosis.先天性肾积水婴儿初始评估中排尿性膀胱尿道造影的使用变异性。
Urology. 2014 May;83(5):1135-8. doi: 10.1016/j.urology.2013.11.011. Epub 2014 Jan 4.
2
Urinary NGAL levels correlate with differential renal function in patients with ureteropelvic junction obstruction undergoing pyeloplasty.尿中性粒细胞明胶酶相关脂质运载蛋白水平与肾盂成形术治疗肾盂输尿管连接部梗阻患者的肾功能差异相关。
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Postnatal evaluation of intrauterine hydronephrosis due to ureteropelvic junction obstruction.
探寻儿童肾盂输尿管连接部梗阻的微创治疗方法:比较性结果的关键文献综述
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Validation of "urinary tract dilation" classification system: Correlation between fetal hydronephrosis and postnatal urological abnormalities.“泌尿道扩张”分类系统的验证:胎儿肾积水与出生后泌尿系统异常之间的相关性。
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Ultrasound evaluation for prediction of outcomes and surgical decision in fetal hydronephrosis.超声评估在胎儿肾积水预后预测及手术决策中的应用
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8
Inpatient interventions that may preclude outpatient open pyeloplasty in infants.可能使婴儿期门诊开放肾盂成形术成为禁忌的住院干预措施。
Int Braz J Urol. 2019 Jan-Feb;45(1):145-149. doi: 10.1590/S1677-5538.IBJU.2018.0252.
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Use of MR Urography in Pediatric Patients.磁共振尿路造影在儿科患者中的应用。
Curr Urol Rep. 2018 Sep 11;19(11):93. doi: 10.1007/s11934-018-0843-7.
10
Diagnostic accuracy of Onen's Alternative Grading System combined with Doppler evaluation of ureteral jets as an alternative in the diagnosis of obstructive hydronephrosis in children.奥嫩替代分级系统结合输尿管喷流多普勒评估在儿童梗阻性肾积水诊断中的诊断准确性,作为一种替代诊断方法。
PeerJ. 2018 May 18;6:e4791. doi: 10.7717/peerj.4791. eCollection 2018.
因肾盂输尿管连接部梗阻导致的宫内肾积水的产后评估。
Acta Cir Bras. 2013;28 Suppl 1:33-6. doi: 10.1590/s0102-86502013001300007.
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Antibiotic prophylaxis for urinary tract infections in antenatal hydronephrosis.产前肾积水的尿路感染抗生素预防。
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Epidermal growth factor and monocyte chemotactic peptide-1: potential biomarkers of urinary tract obstruction in children with hydronephrosis.表皮生长因子和单核细胞趋化蛋白-1:肾积水患儿尿路梗阻的潜在生物标志物。
J Pediatr Urol. 2013 Dec;9(6 Pt A):838-45. doi: 10.1016/j.jpurol.2012.11.011. Epub 2012 Dec 8.
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Postnatal longitudinal evaluation of children diagnosed with prenatal hydronephrosis: insights in natural history and referral pattern.对产前肾积水患儿进行产后纵向评估:自然病史和转诊模式的见解。
Prenat Diagn. 2012 Dec;32(13):1242-9. doi: 10.1002/pd.3989. Epub 2012 Oct 23.
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Children and adolescents with ureteropelvic junction obstruction: is an additional voiding cystourethrogram necessary? Results of a multicenter study.儿童和青少年肾盂输尿管连接部梗阻:是否需要额外的排尿性膀胱尿道造影?一项多中心研究的结果。
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Urinary cytokine profiles in unilateral congenital hydronephrosis.单侧先天性肾积水的尿细胞因子谱。
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Urinary NGAL, cystatin C, β2-microglobulin, and osteopontin significance in hydronephrotic children.尿中性粒细胞明胶酶相关脂质运载蛋白、胱抑素 C、β2-微球蛋白和骨桥蛋白在肾积水患儿中的意义。
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Predictive value of decreased renal pelvis anteroposterior diameter in prone position for prenatally detected hydronephrosis.仰卧位肾盂前后径减小对产前检出肾积水的预测价值。
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