Ogi Kazuhiro, Takabayashi Tetsuji, Sakashita Masafumi, Susuki Dai, Yamada Takechiyo, Manabe Yasuhiro, Fujieda Shigeharu
Division of Otorhinolaryngology, Shinseikai Toyama Hospital, Toyama 939-0243, Japan.
Division of Otorhinolaryngology Head and Neck Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Auris Nasus Larynx. 2014 Dec;41(6):518-22. doi: 10.1016/j.anl.2014.05.020. Epub 2014 Jun 11.
Asian sand dust (ASD), originating in the deserts of Mongolia and China, spreads over large areas and is associated with adverse effects on human health in East Asia, including asthma, heart disease, and some allergic diseases. However, the effect of ASD on patients with seasonal allergic rhinitis caused by Japanese cedar pollen (SAR-JCP), the most common form of allergic rhinitis, remains unclear. The aim of this study was to investigate the effect of ASD on SAR-JCP patients.
A total of 41 patients with SAR-JCP recorded nasal and ocular allergic symptom scores in a diary. We assessed the influence of ASD events on patients with SAR-JCP during the JCP season and before and after the JCP season.
ASD events did not influence nasal and ocular allergy symptoms during the JCP season. Scores for sneezing and runny nose were significantly increased by ASD events in the pre-JCP season. Ocular symptom scores were significantly increased by ASD events in the post-JCP season.
Our results suggest that ASD may exacerbate allergy symptoms even before mass scattering of JCP, which usually does not cause allergic symptoms in patients with SAR-JCP. ASD also induced conjunctivitis symptoms after the JCP season. However, we did not observe any adverse effects of ASD on allergic symptoms during the JCP season.
亚洲沙尘起源于蒙古和中国的沙漠，广泛扩散，与东亚地区对人类健康的不良影响有关，包括哮喘、心脏病和一些过敏性疾病。然而，亚洲沙尘对最常见的过敏性鼻炎形式——日本雪松花粉引起的季节性过敏性鼻炎（SAR-JCP）患者的影响仍不清楚。本研究的目的是调查亚洲沙尘对SAR-JCP患者的影响。
共有41名SAR-JCP患者在日记中记录鼻部和眼部过敏症状评分。我们评估了亚洲沙尘事件在日本雪松花粉季节期间以及该季节之前和之后对SAR-JCP患者的影响。
亚洲沙尘事件在日本雪松花粉季节期间未影响鼻部和眼部过敏症状。在日本雪松花粉季节前，亚洲沙尘事件使打喷嚏和流鼻涕的评分显著增加。在日本雪松花粉季节后，亚洲沙尘事件使眼部症状评分显著增加。
我们的结果表明，即使在日本雪松花粉大量散播之前，亚洲沙尘可能就会加剧过敏症状，而日本雪松花粉通常不会使SAR-JCP患者出现过敏症状。亚洲沙尘还在日本雪松花粉季节后引发了结膜炎症状。然而，我们未观察到亚洲沙尘在日本雪松花粉季节期间对过敏症状有任何不良影响。
