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来自韩国蜂胶的苯丙素酸酯及其抗氧化活性。

Phenylpropanoid acid esters from Korean propolis and their antioxidant activities.

作者信息

Lee In-Kyoung, Han Myung-Suk, Kim Dae-Won, Yun Bong-Sik

机构信息

Division of Biotechnology and Advanced Institute of Environment and Bioscience, Chonbuk National University, 79 Gobong-ro, Iksan-si 570-752, Republic of Korea.

Division of Biotechnology and Advanced Institute of Environment and Bioscience, Chonbuk National University, 79 Gobong-ro, Iksan-si 570-752, Republic of Korea.

出版信息

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3503-5. doi: 10.1016/j.bmcl.2014.05.065. Epub 2014 May 28.

DOI:10.1016/j.bmcl.2014.05.065
PMID:24928402
Abstract

Ten phenylpropanoic acid esters were isolated from an ethanolic extract of Korean propolis. Their structures were elucidated by spectroscopic methods including NMR and ESI-MS. Caffeic acid esters with catechol moiety exhibited significant ABTS and DPPH radical scavenging activity and protective effect against DNA damage by a Fenton reaction.

摘要

从韩国蜂胶的乙醇提取物中分离出10种苯丙酸酯。通过包括核磁共振（NMR）和电喷雾电离质谱（ESI-MS）在内的光谱方法阐明了它们的结构。含有儿茶酚部分的咖啡酸酯表现出显著的2,2'-联氮-双-3-乙基苯并噻唑啉-6-磺酸（ABTS）和1,1-二苯基-2-三硝基苯肼（DPPH）自由基清除活性以及对芬顿反应引起的DNA损伤的保护作用。

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