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神经囊尾蚴病患儿的认知与行为功能障碍:一项横断面研究

Cognitive and behaviour dysfunction of children with neurocysticercosis: a cross-sectional study.

作者信息

Prasad Rajniti, Mishra Om P, Upadhyay Shashi K, Singh Tej B, Singh Utpal Kant

机构信息

Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India

Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.

出版信息

J Trop Pediatr. 2014 Oct;60(5):358-62. doi: 10.1093/tropej/fmu029. Epub 2014 Jun 13.

Abstract

Eighty-three confirmed cases of neurocysticercosis diagnosed as per modified delBrutto criteria were enrolled in the study (Group-I) to observe cognitive and behavioural changes. Controls consisted of two groups: children with idiopathic generalized tonic-clonic seizure (Group-II) and normal children with non-specific cough (Group-III). Cases and controls were subjected to cognitive and behaviour assessment. There was significant difference in the intelligence quotient (IQ) of cases in domains of visual perception, immediate recall, analysis synthesis and reasoning, verbal ability, memory and spatial ability. In the age group of 6-18 years, cases had significantly more behaviour problems than control without seizure, in domains of anxious depressed, withdrawn depressed, somatic problems, social problems and rule-breaking behaviour. Neurocysticercosis causes decline in cognitive function and behaviours in older children, which should be recognized early for appropriate management and to avoid undue parental anxiety.

摘要

按照改良的德尔布鲁托标准确诊的83例神经囊尾蚴病患者被纳入研究(第一组),以观察认知和行为变化。对照组由两组组成:特发性全身性强直阵挛发作儿童(第二组)和有非特异性咳嗽的正常儿童(第三组)。对病例组和对照组进行了认知和行为评估。病例组在视觉感知、即时回忆、分析综合与推理、语言能力、记忆和空间能力等领域的智商(IQ)存在显著差异。在6至18岁年龄组中,病例组在焦虑抑郁、退缩抑郁、躯体问题、社会问题和违规行为等领域的行为问题明显多于无癫痫发作的对照组。神经囊尾蚴病会导致大龄儿童认知功能和行为下降,应尽早识别以便进行适当管理并避免家长过度焦虑。

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