Al Zahrani Hassan, Kyoung Kim Tae, Khalili Korosh, Vlachou Paraskevi, Yu Hojun, Jang Hyun-Jung
Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
Semin Ultrasound CT MR. 2014 Jun;35(3):240-54. doi: 10.1053/j.sult.2013.12.002. Epub 2013 Dec 19.
IgG4-related disease is a systemic disorder that can involve various abdominal organs. Abdominal manifestations include autoimmune pancreatitis, sclerosing cholangitis, gallbladder pseudotumours, multifocal renal abnormalities, retroperitoneal fibrosis, and sclerosing mesenteritis. Radiological appearances of the IgG4-related disease often resemble malignant tumors and other inflammatory processes, potentially leading to unnecessary invasive procedures. Moreover, a timely diagnosis of IgG4-related disease leads to an effective treatment with steroids. Therefore, it is important to understand the spectrum of imaging manifestations of IgG4-related disease and their differentiating features from other diagnoses.
IgG4相关性疾病是一种可累及多种腹部器官的全身性疾病。腹部表现包括自身免疫性胰腺炎、硬化性胆管炎、胆囊假性肿瘤、多灶性肾脏异常、腹膜后纤维化和硬化性肠系膜炎症。IgG4相关性疾病的影像学表现常类似于恶性肿瘤和其他炎症过程,可能导致不必要的侵入性操作。此外,及时诊断IgG4相关性疾病可采用类固醇进行有效治疗。因此,了解IgG4相关性疾病的影像学表现谱及其与其他诊断的鉴别特征非常重要。