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腹部IgG4相关性疾病:一种极具迷惑性的疾病。

IgG4-related disease in the abdomen: a great mimicker.

作者信息

Al Zahrani Hassan, Kyoung Kim Tae, Khalili Korosh, Vlachou Paraskevi, Yu Hojun, Jang Hyun-Jung

机构信息

Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.

Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.

出版信息

Semin Ultrasound CT MR. 2014 Jun;35(3):240-54. doi: 10.1053/j.sult.2013.12.002. Epub 2013 Dec 19.

DOI:10.1053/j.sult.2013.12.002
PMID:24929264
Abstract

IgG4-related disease is a systemic disorder that can involve various abdominal organs. Abdominal manifestations include autoimmune pancreatitis, sclerosing cholangitis, gallbladder pseudotumours, multifocal renal abnormalities, retroperitoneal fibrosis, and sclerosing mesenteritis. Radiological appearances of the IgG4-related disease often resemble malignant tumors and other inflammatory processes, potentially leading to unnecessary invasive procedures. Moreover, a timely diagnosis of IgG4-related disease leads to an effective treatment with steroids. Therefore, it is important to understand the spectrum of imaging manifestations of IgG4-related disease and their differentiating features from other diagnoses.

摘要

IgG4相关性疾病是一种可累及多种腹部器官的全身性疾病。腹部表现包括自身免疫性胰腺炎、硬化性胆管炎、胆囊假性肿瘤、多灶性肾脏异常、腹膜后纤维化和硬化性肠系膜炎症。IgG4相关性疾病的影像学表现常类似于恶性肿瘤和其他炎症过程,可能导致不必要的侵入性操作。此外,及时诊断IgG4相关性疾病可采用类固醇进行有效治疗。因此,了解IgG4相关性疾病的影像学表现谱及其与其他诊断的鉴别特征非常重要。

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引用本文的文献

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Pancreatic cancer, autoimmune or chronic pancreatitis, beyond tissue diagnosis: Collateral imaging and clinical characteristics may differentiate them.胰腺癌、自身免疫性或慢性胰腺炎,超越组织诊断:间接影像学检查和临床特征可对它们进行鉴别。
World J Gastrointest Oncol. 2023 Jun 15;15(6):925-942. doi: 10.4251/wjgo.v15.i6.925.
2
Sclerosing Mesenteritis as an Uncommon Site of Involvement of IgG4-Related Disease: A Case Report With an Updated Review of the Literature.硬化性肠系膜脂膜炎作为IgG4相关疾病少见的受累部位:1例病例报告及文献复习更新
Cureus. 2022 May 16;14(5):e25041. doi: 10.7759/cureus.25041. eCollection 2022 May.
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Abdom Radiol (NY). 2019 Jun;44(6):2111-2115. doi: 10.1007/s00261-019-01944-1.
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Surgical management of isolated mesenteric autoimmune disease: addressing the spectrum of IgG-related disease and sclerosing mesenteritis.孤立性肠系膜自身免疫性疾病的外科治疗:应对IgG相关疾病和硬化性肠系膜炎症的范围
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