Mitamura Yasutaka, Ito Takamichi, Nakano-Nakamura Misa, Uchi Hiroshi, Furue Masutaka
Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Case Rep Dermatol. 2014 May 16;6(2):140-4. doi: 10.1159/000363097. eCollection 2014 May.
Spindle cell melanoma, which is a rare form of melanoma, is clinically and histopathologically difficult to diagnose from a variety of nonmelanocytic spindle cell tumors. We describe a 42-year-old Japanese woman with amelanotic melanoma that comprised spindle cells with positive c-kit and S100A6 staining. The use of c-kit and S100A6 might be useful for improving the diagnosis.
梭形细胞黑色素瘤是黑色素瘤的一种罕见形式,在临床和组织病理学上很难与多种非黑色素细胞性梭形细胞瘤相鉴别。我们描述了一名42岁的日本女性,其无色素性黑色素瘤由c-kit和S100A6染色阳性的梭形细胞组成。使用c-kit和S100A6可能有助于提高诊断水平。