一名无黑斑息肉综合征患者的转移性卵巢性索间质瘤伴环状小管

Metastatic ovarian sex-cord stromal tumor with annular tubules in a patient without Peutz-Jeghers syndrome.

作者信息

Dart Kimi, Schwartzenfeld Ted, Brandes Warren, D'Errico Anthony, Stender Michael

机构信息

Department of Otolaryngology, St. John Oakland Hospital, 27483 Dequindre Rd., Suite 201, Madison Heights, MI 48071, USA.

出版信息

Ear Nose Throat J. 2014 Jun;93(6):E9-E13.

PMID:24932834

Abstract

Sex-cord stromal tumors (SCSTs) with annular tubules (SCTATs) are a small class of ovarian lesions that possess histologic features of both Sertoli and granulosa cells. Approximately one-third of patients with SCTAT also have Peutz-Jaghers syndreome, which makes these cases especially rare. Patients with non-PJS-associated SCTAT make up the remaining two-thirds; 20% of these cases have a metastatic presentation. Metastasis of these tumors to the head and neck region has only been reported in a few instances. In this article we report a case of a 25-year-old woman who presented with "a lump in her throat" and was ultimately diagnosed with SCTAT. We also discuss the current protocols in the diagnosis and treatment of this entity.

摘要

具有环状小管的性索间质肿瘤（SCTAT）是一类少见的卵巢病变，具有支持细胞和颗粒细胞的组织学特征。大约三分之一的SCTAT患者同时患有黑斑息肉综合征，这使得这些病例尤为罕见。非黑斑息肉综合征相关的SCTAT患者占其余的三分之二；其中20%的病例有转移表现。这些肿瘤转移至头颈部区域仅在少数病例中有报道。在本文中，我们报告了一例25岁女性患者，她因“喉咙有肿块”就诊，最终被诊断为SCTAT。我们还讨论了该疾病目前的诊断和治疗方案。