Qian Xiaosen, Liu Yi, Xiao Bing, Gao Li, Li Songlin, Dang Lijie, Si Cuiping, Zhao Lun
Sleep Disorders Center, Civil Aviation General Hospital, Beijing, China.
Sleep Disorders Center, Civil Aviation General Hospital, Beijing, China.
Int J Psychophysiol. 2014 Sep;93(3):311-5. doi: 10.1016/j.ijpsycho.2014.06.004. Epub 2014 Jun 14.
In the present article, we tested an optimal vMMN paradigm allowing one to obtain vMMNs for several visual attributes in a short time. vMMN responses to changes in color, duration, orientation, shape, and size were compared between the traditional 'oddball' paradigm (a single type of visual change in each sequence) and the optimal paradigm in which all the 5 types of changes appeared within the same sequence. The vMMNs obtained in the optimal paradigm were equal or larger in amplitude to those in the traditional vMMN paradigm. The optimal paradigm can provide 5 different vMMNs in the same time in which usually only one MMN is obtained. This short objective measure could putatively be used as an index for visual cognition function especially in clinical research.
在本文中，我们测试了一种优化的视觉失匹配负波（vMMN）范式，该范式能够让人在短时间内获取针对多种视觉属性的vMMN。我们比较了传统“oddball”范式（每个序列中只有单一类型的视觉变化）和优化范式（所有5种类型的变化出现在同一序列中）下vMMN对颜色、时长、方向、形状和大小变化的反应。在优化范式中获得的vMMN的波幅与传统vMMN范式中的相等或更大。优化范式能够在通常只能获得一个MMN的相同时间内提供5种不同的vMMN。这种简短的客观测量方法可能被用作视觉认知功能的指标，特别是在临床研究中。
