Information Engineering Department, University of Florence, Via S. Marta n. 3, 50139 Firenze, Italy.
Information Engineering Department, University of Florence, Via S. Marta n. 3, 50139 Firenze, Italy.
Ultrasonics. 2014 Sep;54(7):2006-14. doi: 10.1016/j.ultras.2014.05.012. Epub 2014 Jun 2.
Maximum blood velocity estimates are frequently required in diagnostic applications, including carotid stenosis evaluation, arteriovenous fistula inspection, and maternal-fetal examinations. However, the currently used methods for ultrasound measurements are inaccurate and often rely on applying heuristic thresholds to a Doppler power spectrum. A new method that uses a mathematical model to predict the correct threshold that should be used for maximum velocity measurements has recently been introduced. Although it is a valuable and deterministic tool, this method is limited to parabolic flows insonated by uniform pressure fields. In this work, a more generalized technique that overcomes such limitations is presented. The new approach, which uses an extended Doppler spectrum model, has been implemented in an experimental set-up based on a linear array probe that transmits defocused steered waves. The improved model has been validated by Field II simulations and phantom experiments on tubes with diameters between 2mm and 8mm. Using the spectral threshold suggested by the new model significantly higher accuracy estimates of the peak velocity can be achieved than are now clinically attained, including for narrow beams and non-parabolic velocity profiles. In particular, an accuracy of +1.2±2.5 cm/s has been obtained in phantom measurements for velocities ranging from 20 to 80 cm/s. This result represents an improvement that can significantly affect the way maximum blood velocity is investigated today.
最大血流速度估计在诊断应用中经常需要,包括颈动脉狭窄评估、动静脉瘘检查和胎儿检查。然而,目前用于超声测量的方法不准确,并且通常依赖于将启发式阈值应用于多普勒功率谱。最近引入了一种使用数学模型预测用于最大速度测量的正确阈值的新方法。尽管这是一种有价值的确定性工具,但该方法仅限于被均匀压力场照射的抛物线流。在这项工作中,提出了一种更通用的技术来克服这些限制。新方法使用扩展的多普勒频谱模型,已在基于线性阵列探头的实验装置中实现,该探头发射离焦的定向波。改进的模型已通过 Field II 模拟和直径为 2mm 至 8mm 的管的体模实验进行了验证。使用新模型建议的频谱阈值,可以实现比目前临床应用更高的峰值速度准确性估计,包括窄波束和非抛物线速度分布。特别是,在体模测量中,对于 20 至 80cm/s 的速度范围,获得了+1.2±2.5cm/s 的准确度。该结果代表了一种改进,可以显著影响当今最大血流速度的研究方式。