与甲麦角新碱长期治疗相关的心脏瓣膜病：1 例报告。

Valvular heart disease associated with long-term treatment by methysergide: a case report.

机构信息

Service de Pharmacologie clinique, Centre régional de Pharmacovigilance de Picardie, Centre hospitalier universitaire Sud d'Amiens, Amiens, France - INSERM U 1088, Université de Picardie, Amiens, France.

Service de Cardiologie, Centre hospitalier universitaire Sud d'Amiens, Amiens, France.

出版信息

Therapie. 2014 May-Jun;69(3):255-7. doi: 10.2515/therapie/2014030. Epub 2014 Jun 18.

DOI:10.2515/therapie/2014030

PMID:24934823

Abstract

This case report concerns a woman treated continuously since at least 10 years by methysergide for cluster headache. The echocardiographic and histological features of the severe valve fibrosis presented by this patient are very similar to those described with 5 HT(2B) receptors agonistic drugs.

摘要

本病例报告涉及一名女性患者，自至少 10 年前开始一直接受麦角乙脲治疗丛集性头痛。该患者表现出的严重瓣膜纤维化的超声心动图和组织学特征与那些与 5-HT（2B）受体激动剂药物描述的非常相似。