[粘质沙雷氏菌骨髓炎作为慢性肉芽肿病的首发表现]

[Serratia marcescens osteomyelitis as the first manifestation of chronic granulomatous disease].

作者信息

Ben Abdallah Chabchoub R, Maalej B, Gargouri L, Turki F, Majdoub I, Keskes H, Barbouche R, Ben Halima N, Mahfoudh A

机构信息

Service de pédiatrie, urgences et réanimation pédiatriques, CHU Hédi Chaker, Sfax, Tunisie.

出版信息

Arch Pediatr. 2014 Jul;21(7):754-6. doi: 10.1016/j.arcped.2014.04.023. Epub 2014 Jun 13.

DOI:10.1016/j.arcped.2014.04.023

PMID:24935451

Abstract

Chronic granulomatous disease is a rare, primary immunodeficiency disorder characterized by a defect in oxidative metabolism in phagocytes and recurrent bacterial and fungal infections. We report a case in a 2-month-old infant admitted with metacarpic osteomyelitis due to Serratia marcescens. Chronic granulomatous disease is rare but must be considered in cases of uncommon or atypical infection.

摘要

慢性肉芽肿病是一种罕见的原发性免疫缺陷疾病，其特征为吞噬细胞氧化代谢缺陷以及反复发生的细菌和真菌感染。我们报告一例2个月大婴儿因粘质沙雷菌导致掌骨骨髓炎入院的病例。慢性肉芽肿病很罕见，但在出现不常见或非典型感染的病例中必须予以考虑。