Liu Yue, Wang Xiao-ping, Wu Bin, Hu Yue, Dou Xia, Sun Hong-ying, Ding Ya-tong, Zhang Xin
Department of Stomatology, Huashan Hospital, Fudan University. Shanghai 200040;China.E-mail:
Shanghai Kou Qiang Yi Xue. 2014 Apr;23(2):143-8.
To compare the sensitivity of different dental metal materials, in order to provide references for choosing of dental metal materials.
Patch test was performed on 92 patients wearing dental metal prosthesis. Pearson Chi-square test, corrected Chi-square test and Fisher exact test were used for statistical analysis with SPSS17.0 software package.
(1)The sensitivity rates of different metal materials were different. The allergy rate of nickel (Ni) was the highest (22.8%), while the allergy rate of aluminum (Al) was 0. (2)More women were allergic to both palladium (Pd) and nickel (Ni) than men with significant difference (P>0.05). (3)Women with ear piercing were more allergic to nickel (Ni), but there was no significant correlation between ear piercing and nickel allergy (P>0.05).(4)There was cross reaction between nickel(Ni)and palladium (Pd), 83.3% of palladium (Pd) allergy patients were allergic to nickel (Ni), while 47.6% of nickel(Ni) allergy patients were allergic to palladium (Pd). (5)Patch test had a delayed reaction.
Dental metal materials have certain allergies, women are more allergic to both palladium (Pd) and nickel (Ni) than men, with significant difference. Patch test may have a delayed reaction. If necessary, observation for 96 h, 7 days or even longer time, are needed to exclude false positivity. Supported by Research Fund of Science and Technology Committee of Shanghai Municipality (10411950900).
比较不同牙科金属材料的敏感性，为牙科金属材料的选择提供参考。
对92例佩戴牙科金属修复体的患者进行斑贴试验。采用Pearson卡方检验、校正卡方检验和Fisher确切概率法，用SPSS17.0软件包进行统计学分析。
（1）不同金属材料的敏感率不同。镍（Ni）的过敏率最高（22.8%），而铝（Al）的过敏率为0。（2）女性对钯（Pd）和镍（Ni）过敏的人数均多于男性，差异有统计学意义（P>0.05）。（3）有耳洞的女性对镍（Ni）更易过敏，但耳洞与镍过敏之间无显著相关性（P>0.05）。（4）镍（Ni）与钯（Pd）之间存在交叉反应，83.3%的钯（Pd）过敏患者对镍（Ni）过敏，而47.6%的镍（Ni）过敏患者对钯（Pd）过敏。（5）斑贴试验有延迟反应。
牙科金属材料存在一定的过敏情况，女性对钯（Pd）和镍（Ni）的过敏率均高于男性，差异有统计学意义。斑贴试验可能有延迟反应，必要时需观察96小时、7天甚至更长时间以排除假阳性。上海市科学技术委员会科研基金资助（10411950900）。
