Augthun M, Lichtenstein M, Kammerer G
Klinik für Zahnarztliche Prothetik der Medizinischen Fakultat der TWTH Aachen.
Dtsch Zahnarztl Z. 1990 Aug;45(8):480-2.
Epicutaneous tests with test solutions of the European standard series and palladium chloride (1%) were performed in 486 patients of the University Hospital for Dermatology in Aachen. 17.9% of the patients exhibited Ni, 8.6% Co, 7.4% Pd and 4.1% Cr allergy. In 18 of 36 patients with a positive patch test reaction a further epicutaneous and epimucosal testing with metallic plates of pure palladium and a palladium alloy was performed. In 34 cases a positive skin reaction to palladium chloride was combined with a positive skin reaction to nickel sulphate. Only in one case was it possible to demonstrate an allergic reaction to a palladium metallic plate, which was tested additionally in artificial saliva. The results show that a dental alloy envisaged for use should be tested in an epicutaneous test, if the patient shows a positive reaction to the metallic salt solution. In case of positive patch tests to nickel sulphate, dental palladium alloys should not be used as an alternative unless sensitivity to palladium has been tested.
在亚琛大学医院皮肤科的486名患者中，使用欧洲标准系列测试溶液和氯化钯（1%）进行了表皮试验。17.9%的患者对镍过敏，8.6%对钴过敏，7.4%对钯过敏，4.1%对铬过敏。在36例斑贴试验反应阳性的患者中，有18例进一步使用纯钯金属板和钯合金进行了表皮和粘膜测试。在34例中，对氯化钯的阳性皮肤反应与对硫酸镍的阳性皮肤反应同时出现。仅在1例中，证实了对钯金属板有过敏反应，该金属板还在人工唾液中进行了测试。结果表明，如果患者对金属盐溶液反应呈阳性，设想使用的牙科合金应进行表皮试验。如果对硫酸镍斑贴试验呈阳性，除非已测试对钯的敏感性，否则不应使用牙科钯合金作为替代品。
