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Placental and decidual u-PA, t-PA, PAI-1 and PAI-2 concentrations, as affected by cervical dilatation with laminaria tents or Hegar dilators.

作者信息

Jonasson A, Larsson B, Lecander I, Astedt B

机构信息

Department of Obstetrics, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden.

出版信息

Thromb Res. 1989 Jan 15;53(2):91-7. doi: 10.1016/0049-3848(89)90371-x.

DOI:10.1016/0049-3848(89)90371-x
PMID:2493685
Abstract

The effect of cervical dilatation on PA and PAI concentrations was compared in a laminaria tent group and a mechanical dilatation (control) group. In both groups, u-PA and t-PA were found to be present both in decidual and placental tissue. Values for PAI-1 in the decidua were higher in the laminaria tent group than in controls, and those for PAI-2 in the placenta were lower. These findings provide support for the contention that cervical dilatation with laminaria tents may result in partial detachment of the placenta.

摘要

相似文献

1
Placental and decidual u-PA, t-PA, PAI-1 and PAI-2 concentrations, as affected by cervical dilatation with laminaria tents or Hegar dilators.
Thromb Res. 1989 Jan 15;53(2):91-7. doi: 10.1016/0049-3848(89)90371-x.
2
The effect of cervical dilatation by laminaria tent in first trimester legal abortions on blood loss related to fibrinolytic activity in the decidua and placenta.妊娠早期合法堕胎时使用海藻棒扩张宫颈对与蜕膜和胎盘纤溶活性相关的失血的影响。
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Should we use prostaglandins, tents or progesterone antagonists for cervical ripening before first trimester abortion?在孕早期流产前进行宫颈成熟时,我们应该使用前列腺素、宫颈扩张球囊还是孕激素拮抗剂?
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Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.与纤维蛋白结合的1型纤溶酶原激活物抑制剂(PAI-1)与组织型纤溶酶原激活物(t-PA)或尿激酶型纤溶酶原激活物(u-PA)之间的相互作用。t-PA的指状结构域和kringle-2结构域介导t-PA/PAI-1复合物与纤维蛋白的结合。
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引用本文的文献

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A Review of the Mechanism of Action and Clinical Applications of Osmotic Dilators for Cervical Ripening in the Induction of Labor and in Gynecology Procedures.经阴道前列腺素制剂用于足月妊娠引产及妇科手术的临床应用及作用机制研究进展
Med Sci Monit. 2023 Jun 27;29:e940127. doi: 10.12659/MSM.940127.
2
Expression of tissue type and urokinase type plasminogen activators as well as plasminogen activator inhibitor type-1 and type-2 in human and rhesus monkey placenta.组织型和尿激酶型纤溶酶原激活剂以及纤溶酶原激活剂抑制剂-1和-2在人和恒河猴胎盘中的表达
J Anat. 1999 Feb;194 ( Pt 2)(Pt 2):183-95. doi: 10.1046/j.1469-7580.1999.19420183.x.