Fleming C R
Division of Gastroenterology and Internal Medicine, Mayo Clinic, Jacksonville, FL 32224.
Am J Clin Nutr. 1989 Mar;49(3):573-9. doi: 10.1093/ajcn/49.3.573.
Clinical expressions of iron, zinc, and copper deficiencies associated with total parenteral nutrition (TPN) prompted recommendations by the Nutritional Advisory Group of the American Medical Association's Department of Foods and Nutrition for trace element additives for parenteral use. In the 11 years since that conference, home parenteral nutrition (HPN) has gained increasing popularity as a means to support patients with gut failure for many years. Observations in the long-term patients on HPN confirmed the risks of Fe, Zn, and Cu deficiencies and provided new evidence for clinically significant deficiencies of selenium, chromium, and molybdenum.
与全胃肠外营养（TPN）相关的铁、锌和铜缺乏的临床表现促使美国医学协会食品与营养部营养咨询小组提出了关于肠外使用微量元素添加剂的建议。自那次会议后的11年里，家庭肠外营养（HPN）作为一种长期支持肠道功能衰竭患者的方法越来越受欢迎。对长期接受HPN治疗的患者的观察证实了铁、锌和铜缺乏的风险，并为硒、铬和钼的临床显著缺乏提供了新证据。
