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微血管减压术治疗复发性三叉神经痛。

Microvascular decompression for recurrent trigeminal neuralgia.

作者信息

Gu Weiting, Zhao Weiguo

机构信息

Department of Neurosurgery, Rui Jin Hospital North, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Department of Neurosurgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, People's Republic of China.

出版信息

J Clin Neurosci. 2014 Sep;21(9):1549-53. doi: 10.1016/j.jocn.2013.11.042. Epub 2014 Jun 15.

Abstract

Recurrence of trigeminal neuralgia (TN) symptoms after microvascular decompression (MVD) is a challenge for neurosurgeons. This study evaluates the indication, efficacy and safety of re-do MVD. We retrospectively reviewed consecutive patients who underwent MVD for TN from January 2000 to June 2012. The parameters of study interest were pre-operative magnetic resonance tomographic angiography (MRTA) findings and operative findings. Pain outcome was scored using the Barrow Neurological Institute (BNI) grading scale. Twelve patients underwent re-do MVD following recurrence of pain. Vascular compression was detected on pre-operative MRTA images in eight patients, a small mass was found in two patients, and pre-operative imaging was negative in two patients. Of the eight patients with a positive finding of arterial conflict, a vascular loop was identified intra-operatively in five patients (62.5%); in two (25.0%) a small granuloma filled with Teflon fibers was found compressed the trigeminal nerve; and in one patient (12.5%) only dense arachnoid adhesions were found around the trigeminal nerve. For the two patients with mass compression on MRTA images, a granuloma was found during operation. Neurovascular compression was found in the two patients with negative preoperative MRTA images. Re-do MVD is a safe and effective treatment for recurrent TN when indicated by a prolonged pain-free period following the first surgery.

摘要

微血管减压术(MVD)后三叉神经痛(TN)症状复发对神经外科医生来说是一项挑战。本研究评估再次进行MVD的适应症、疗效和安全性。我们回顾性分析了2000年1月至2012年6月期间因TN接受MVD的连续患者。研究关注的参数为术前磁共振断层血管造影(MRTA)结果和手术结果。疼痛结局采用巴罗神经学研究所(BNI)分级量表评分。12例患者在疼痛复发后接受了再次MVD。术前MRTA图像上检测到血管压迫8例,发现小肿块2例,术前影像学检查阴性2例。在8例动脉冲突阳性的患者中,术中发现血管襻5例(62.5%);2例(25.0%)发现充满特氟龙纤维的小肉芽肿压迫三叉神经;1例(12.5%)仅在三叉神经周围发现致密的蛛网膜粘连。对于MRTA图像上有肿块压迫的2例患者,术中发现肉芽肿。术前MRTA图像阴性的2例患者发现神经血管压迫。当首次手术后无痛期延长提示有适应症时,再次MVD是复发性TN的一种安全有效的治疗方法。

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