Alaeddini Mojgan, Barghammadi Roohollah, Eshghyar Nosratollah, Etemad-Moghadam Shahroo
Assistant Professor, Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Dentist, Department of Oral and Maxillofacial Pathology, Tehran University of Medical Sciences, Tehran, Iran.
J Contemp Dent Pract. 2014 Jan 1;15(1):1-7. doi: 10.5005/jp-journals-10024-1478.
The aim of the present study was to analyze data on the characteristics of tongue lesions in dental patients seeking care at the Oral Pathology Service of Tehran University of Medical Sciences, from 1985-2010.
Demographic data and histopathologic diagnoses were recorded for all lesions that were documented as occurring on the tongue according to the patient records in our department. Statistical analysis included chi-square, t-, and Fisher's exact tests. A 95% confidence interval (CI) was calculated, and p < 0.05 was considered significant.
Tongue lesions constituted 6.3% of all received specimens which included 46 different defects. The most common lesions were lichen planus (LP), irritation fibroma (IF), squamous cell carcinoma (SCC) and pemphigus vulgaris (PV). Tongue lesions were significantly more common in women compared to men (CI = 0.65-0.94, p = 0.02). Mean age (47 years) did not differ between male and female subjects (CI = -2.49 - 3.93, p = 0.06). The dorsal surface followed by the lateral aspect was the most common site for tongue lesions.
It seems that dental practitioners should be perceptive of LP, IF, SCC and PV, when examining the tongue. Histopathologic analysis is essential for achieving final diagnosis in a considerable number of lesions that commonly occur on this organ. Clinical significance: Access to demographic/prevalence data in different populations may be useful in clinical settings and could be complimented by histopathologic diagnosis in most instances. The present findings can be compared with those obtained from other epidemiologic studies in this field resulting in valuable data which may be used in several types of investigations. .
本研究旨在分析1985年至2010年期间在德黑兰医科大学口腔病理科就诊的牙科患者舌部病变特征的数据。
根据我们科室的患者记录，对所有记录在案的发生于舌部的病变的人口统计学数据和组织病理学诊断进行记录。统计分析包括卡方检验、t检验和费舍尔精确检验。计算95%置信区间（CI），p<0.05被认为具有统计学意义。
舌部病变占所有接收标本的6.3%，其中包括46种不同的病变。最常见的病变为扁平苔藓（LP）、刺激性纤维瘤（IF）、鳞状细胞癌（SCC）和寻常型天疱疮（PV）。女性舌部病变明显比男性更常见（CI=0.65-0.94，p=0.02）。男性和女性受试者的平均年龄（47岁）无差异（CI=-2.49-3.93，p=0.06）。舌背其次是舌侧面是舌部病变最常见的部位。
看来牙科医生在检查舌部时应留意LP、IF、SCC和PV。组织病理学分析对于在该器官常见的相当数量的病变中实现最终诊断至关重要。临床意义：获取不同人群的人口统计学/患病率数据在临床环境中可能有用，并且在大多数情况下可以通过组织病理学诊断加以补充。本研究结果可与该领域其他流行病学研究的结果进行比较，从而得出可用于多种类型调查的有价值数据。
