Kasahara Masayuki, Shoji Nobuyuki, Morita Tetsuya, Shimizu Kimiya
Department of Ophthalmology, Graduate School of Medical Science, School of Medicine, Kitasato University, 1-15-1 Kitasato, Minamiku, Sagamihara, Kanagawa, 252-0373, Japan,
Jpn J Ophthalmol. 2014 Sep;58(5):396-401. doi: 10.1007/s10384-014-0329-1. Epub 2014 Jun 19.
To determine the differences in scleral shape between the superonasal and superotemporal quadrants, the sites of scleral flap creation in trabeculectomy, using anterior segment optical coherence tomography (OCT).
Thirty-four right eyes of 34 enrolled subjects without ocular disease, with the exception of cataract or ametropia, were studied. Mean patient age was 63.2 ± 15.9 (standard deviation) years (range 28-84 years). The same examiner captured all images using anterior segment swept source OCT. The mean measurements were calculated from three images captured for each eye, 60° from the horizontal line passing through the pupillary center in the superonasal and superotemporal sclera. The radius of the scleral surface curvature and the area of the convex part of the sclera between the superonasal and the superotemporal quadrants were determined using image analysis software and the paired t test.
The radius of the scleral curvature was significantly different in the superonasal quadrant and superotemporal quadrant (34.3 ± 12.6 vs. 18.3 ± 3.6 mm, respectively; P < 0.001). The area of the convex part of the sclera was also significantly different in the superonasal and superotemporal quadrants (0.36 ± 0.1 vs. 0.57 ± 0.1 mm(2), respectively; P < 0.001).
Anterior segment OCT analysis of the scleral shape revealed a more gradual scleral gradient in the superonasal quadrant compared with the superotemporal quadrant.
使用眼前节光学相干断层扫描（OCT）确定小梁切除术中巩膜瓣制作部位——鼻上象限和颞上象限之间巩膜形状的差异。
对34名入组受试者的34只右眼进行研究，这些受试者除白内障或屈光不正外无眼部疾病。患者平均年龄为63.2±15.9（标准差）岁（范围28 - 84岁）。由同一名检查者使用眼前节扫频源OCT采集所有图像。对每只眼睛从穿过瞳孔中心的水平线在鼻上和颞上巩膜处分别60°方向采集的三张图像进行平均测量计算。使用图像分析软件和配对t检验确定鼻上象限和颞上象限之间巩膜表面曲率半径以及巩膜凸面部分的面积。
鼻上象限和颞上象限的巩膜曲率半径有显著差异（分别为34.3±12.6与18.3±3.6mm；P<0.001）。鼻上象限和颞上象限的巩膜凸面部分面积也有显著差异（分别为0.36±0.1与0.57±0.1mm²；P<0.001）。
眼前节OCT对巩膜形状的分析显示，与颞上象限相比，鼻上象限的巩膜梯度更为平缓。
