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尼日利亚西南部一家三级医院对十二指肠溃疡穿孔治疗的综述。

A review of the management of perforated duodenal ulcers at a tertiary hospital in south western Nigeria.

作者信息

Etonyeaku A C, Agbakwuru E A, Akinkuolie A A, Omotola C A, Talabi A O, Onyia C U, Kolawole O A, Aladesuru O A

机构信息

Department of Surgery, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria.

出版信息

Afr Health Sci. 2013 Dec;13(4):907-13. doi: 10.4314/ahs.v13i4.7.

Abstract

BACKGROUND

Gastro-duodenal perforations are common and may complicate peptic ulcer disease. Management is often by surgical closure.

OBJECTIVE

To determine the patterns of presentation and mode of management of duodenal ulcer perforations.

METHODS

Retrospective review of patients with duodenal ulcer perforations seen at the Obafemi Awolowo University Teaching Hospital between June 2001 and July 2011. Patients' records were reviewed for demography, duration of disease, probable risk factors, type of surgery and complications. Data obtained was analyzed using SPSS 15.0.

RESULT

Forty- five patients were reviewed. There were 37 males (82.2%). Mean age was 39.7years (range 15-78years). There were 10 (22.6%) students and 8(17.8%) farmers. NSAIDs abuse (11), previous peptic ulcer disease (2), and no prior dyspeptic symptoms (20) constituted 24.4%, 4.4% and 44.4% respectively of cases. Seven (16%) patients presented less than 24 hours of onset of illness. Forty one perforations (91.1%) involved the first part of duodenum. Twenty two (49%) patients had Graham's omental patch. We had one (2.2%) failed repair and six (13.3%) mortalities.

CONCLUSION

Late presentation of duodenal ulcer perforation is common with high mortality. Pragmatic surgical intervention with Graham's omentopexy with broad spectrum antibiotics is still commonly practiced.

摘要

背景

胃十二指肠穿孔很常见,可能使消化性溃疡病复杂化。治疗通常采用手术缝合。

目的

确定十二指肠溃疡穿孔的临床表现模式和治疗方式。

方法

回顾性分析2001年6月至2011年7月在奥巴费米·阿沃洛沃大学教学医院就诊的十二指肠溃疡穿孔患者。查阅患者记录,了解人口统计学资料、病程、可能的危险因素、手术类型和并发症。使用SPSS 15.0对获得的数据进行分析。

结果

共回顾了45例患者。男性37例(82.2%)。平均年龄39.7岁(范围15 - 78岁)。学生10例(22.6%),农民8例(17.8%)。滥用非甾体抗炎药(11例)、既往有消化性溃疡病(2例)、无既往消化不良症状(20例)分别占病例的24.4%、4.4%和44.4%。7例(16%)患者发病后不到24小时就诊。41例穿孔(91.1%)累及十二指肠第一部。22例(49%)患者采用了格雷厄姆网膜修补术。有1例(2.2%)修补失败,6例(13.3%)死亡。

结论

十二指肠溃疡穿孔就诊延迟很常见,死亡率高。采用格雷厄姆网膜固定术并联合广谱抗生素进行务实的手术干预仍是常用的治疗方法。

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