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射频消融与A型肉毒毒素治疗咬肌肥大的疗效与安全性对比研究。

A comparative study of the efficacy and safety of radiofrequency ablation and botulinum toxin A in treating masseteric hypertrophy.

作者信息

Huang Jin-Long, Chen Gang, Chen Xiao-Dong, Zhou Bing-Rong, Luo Dan

机构信息

Department of Esthetic Plastic Surgery, The First Affiliated Hospital of Nanjing University of TCM, Nanjing, Jiangsu 210029, P.R. China.

Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.

出版信息

Exp Ther Med. 2014 May;7(5):1203-1208. doi: 10.3892/etm.2014.1552. Epub 2014 Feb 17.

DOI:10.3892/etm.2014.1552
PMID:24940412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3991521/
Abstract

The aim of the present study was to evaluate the effects of two treatments for masseteric hypertrophy. In total, 24 patients with masseteric hypertrophy were enrolled in this study. Patients were randomly divided into two groups: 12 individuals were treated with radiofrequency (RF) ablation and 12 patients received an injection of botulinum toxin A. The thickness of the masseter muscle under tension was measured using ultrasound and clinical photographs were captured prior to treatment and at 6 and 12 months following treatment. Complications were observed during 12-month follow-up. In the group injected with botulinum toxin A, masseteric muscle thickness decreased to the lowest point 6 months after the injections but increased until 12 months after injection. However, in the group treated with RF ablation, muscle thickness decreased steadily over the 12 months following surgery. Therefore, the results of the present study indicated that the effect of RF ablation on the thickness of the masseter muscle may be much larger than that obtained following injection with botulinum toxin A.

摘要

本研究的目的是评估两种治疗咬肌肥大的效果。共有24例咬肌肥大患者纳入本研究。患者被随机分为两组:12例接受射频(RF)消融治疗,12例接受A型肉毒毒素注射。使用超声测量紧张状态下咬肌的厚度,并在治疗前以及治疗后6个月和12个月拍摄临床照片。在12个月的随访期间观察并发症。在注射A型肉毒毒素的组中,咬肌厚度在注射后6个月降至最低点,但在注射后12个月时增加。然而,在接受射频消融治疗的组中,术后12个月肌肉厚度持续下降。因此,本研究结果表明,射频消融对咬肌厚度的影响可能比注射A型肉毒毒素后获得的效果大得多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/ecb13d83dd70/ETM-07-05-1203-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/9e6dbef8e790/ETM-07-05-1203-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/7a0de852931d/ETM-07-05-1203-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/53b1a60c29bc/ETM-07-05-1203-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/55164ce08d40/ETM-07-05-1203-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/3b433b539512/ETM-07-05-1203-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/ecb13d83dd70/ETM-07-05-1203-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/9e6dbef8e790/ETM-07-05-1203-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/7a0de852931d/ETM-07-05-1203-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/53b1a60c29bc/ETM-07-05-1203-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/55164ce08d40/ETM-07-05-1203-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/3b433b539512/ETM-07-05-1203-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afaa/3991521/ecb13d83dd70/ETM-07-05-1203-g05.jpg

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本文引用的文献

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Use of botulinum toxin (botox) in the management of masseter muscle hypertrophy: a simplified technique.肉毒杆菌毒素(保妥适)在咬肌肥大治疗中的应用:一种简化技术。
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