Babu Kalpana, Mukhopadhyay Moupia, Bhat Soumya S, Chinmayee Jt
Vittala International Institute of Ophthalmology, Bangalore 560085, India ; Prabha Eye Clinic and Research Centre, 504, 40th Cross, Jayanagar 8th Block, Bangalore 560070, India.
J Ophthalmic Inflamm Infect. 2014 May 22;4:12. doi: 10.1186/1869-5760-4-12. eCollection 2014.
Orbital tuberculosis (OTb) is rare and may be regarded as a manifestation of extrapulmonary tuberculosis. We report an interesting case series of six patients with varied presentations of orbital and adnexal tuberculosis in a South Indian patient population.
A retrospective, interventional case series of six patients diagnosed with orbital and adnexal tuberculosis on the basis of clinical, radiological and histopathological evaluations between 2010 and 2013 was performed. Among the six patients with histopathologically proven OTb, five were women. The varied presentations included tubercular dacryoadenitis (two cases), classical periostitis (two cases), OTb with bone involvement (one case) and ocular adnexal tuberculosis (one case). Systemic involvement was seen in one case. All cases were treated with a regimen of antitubercular therapy (ATT).
OTb, though rare, should form a part of the differential diagnosis of orbital lesions in a high tuberculosis (TB) endemic country like ours. Biopsy still remains the mainstay of diagnosis.
眼眶结核（OTb）较为罕见，可被视为肺外结核的一种表现形式。我们报告了一组有趣的病例，共6例患者，来自印度南部，均表现出不同类型的眼眶及附属器结核。
对2010年至2013年间，基于临床、放射学及组织病理学评估确诊为眼眶及附属器结核的6例患者进行了一项回顾性、干预性病例研究。在6例经组织病理学证实为OTb的患者中，5例为女性。其表现形式多样，包括结核性泪腺炎（2例）、典型骨膜炎（2例）、伴有骨质受累的OTb（1例）及眼附属器结核（1例）。1例出现全身受累情况。所有病例均接受了抗结核治疗（ATT）方案。
在像我国这样结核病（TB）高发的国家，OTb虽罕见，但应作为眼眶病变鉴别诊断的一部分。活检仍是诊断的主要手段。
