男性泌尿生殖道同步原发性恶性肿瘤。
Synchronous primary malignancies of the male urogenital tract.
作者信息
Qarro Abdelmounaim, Ammani Abdelghani, Bazine Khalil, Najoui Mohammed, Samir Jamaleddine, Alami Mohammed
机构信息
Department of Urology, Military Hospital Moulay Ismail, Meknes, Morocco.
出版信息
Can Urol Assoc J. 2014 May;8(5-6):E353-5. doi: 10.5489/cuaj.1532.
The finding of prostate cancer after a cystoprostatectomy for a bladder tumour can occur in up to 70% of cases. The incidence of prostate cancer in patients with a bladder tumour is 18 times higher than in the general population; moreover, the incidence of bladder cancer in patients with prostate cancer is 19 times higher than in the general population. This association can be explained by the common embryological origin of these organs, with molecular similarities. Other similarities between these two cancers are noted. They are multifocal and may be secondary to urinary stasis. However, this association does not seem responsible for an increased risk of progression of both diseases. The prognosis is related to the extension of each cancer. The stage and grade of bladder cancer are, in terms of prognosis, greater than those of prostate cancer. Most often, this is insignificant prostate cancer. Despite this, the prostate-specific antigen test should be administered to monitor patients after cystoprostatectomy.
在因膀胱肿瘤行膀胱前列腺切除术后发现前列腺癌的情况在高达70%的病例中都可能出现。膀胱肿瘤患者中前列腺癌的发病率比普通人群高18倍；此外，前列腺癌患者中膀胱癌的发病率比普通人群高19倍。这种关联可以用这些器官共同的胚胎学起源以及分子相似性来解释。这两种癌症之间还存在其他相似之处。它们多灶性，可能继发于尿潴留。然而，这种关联似乎并不会导致这两种疾病进展风险增加。预后与每种癌症的范围有关。就预后而言，膀胱癌的分期和分级比前列腺癌更重要。大多数情况下，这是无明显意义的前列腺癌。尽管如此，膀胱前列腺切除术后仍应进行前列腺特异性抗原检测以监测患者。
Zotero 插件