St Vincent's Hospital, Mental Health Research Institute, University of Melbourne, Melbourne, Australia.
Int J Psychiatry Clin Pract. 2007;11(4):279-84. doi: 10.1080/13651500701246088.
Objective. This pilot study aimed to determine whether a group based psychosocial intervention reduced rates of relapse, improved function and quality of life in people with bipolar disorder. Method. Patients with a diagnosis of bipolar disorder, types I and II were recruited in the Geelong Region of Victoria. Patients were assessed at baseline for psychiatric status, mood episode, function, and medication adherence. They were randomly assigned to either the intervention arm, a 12-week, structured group-based therapy as an adjunct to treatment as usual or the control arm, which consisted of treatment as usual, plus weekly phone calls. Participants were then followed up for a period of 3 months and assessed by a researcher blinded to treatment and control interventions. Results. Functioning as measured by the Global Assessment of Functioning (GAF) was significantly improved in the intervention group (P=0.008). The social relationships subscale on the (WHOQoL-BREF) showed significant results (P<0.05 level). There was also a positive trend in reduction of relapses in the intervention group. Conclusion. The use of a group intervention for bipolar disorder as an adjunct to usual treatment has potential benefits, both in reduction of relapse and improvement in functionality, and may be a cost effective way of delivering psychosocial treatments.
目的。本试点研究旨在确定基于群体的心理社会干预是否能降低双相情感障碍患者的复发率，改善其功能和生活质量。
方法。在维多利亚州的吉朗地区招募了被诊断为 I 型和 II 型双相情感障碍的患者。在基线评估时，对患者的精神状态、情绪发作、功能和药物依从性进行评估。他们被随机分配到干预组或对照组，干预组接受为期 12 周的结构化基于群体的治疗作为常规治疗的辅助治疗，对照组为常规治疗加每周电话随访。然后，对参与者进行为期 3 个月的随访，并由对治疗和对照干预措施均不知情的研究人员进行评估。
结果。功能评估采用总体功能评估（GAF），干预组的功能显著改善（P=0.008）。（WHOQoL-BREF）的社会关系子量表也显示出显著的结果（P<0.05 水平）。干预组的复发率也呈下降趋势。
结论。将群体干预用于双相情感障碍作为常规治疗的辅助治疗具有潜在的益处，既能降低复发率，又能改善功能，并且可能是一种经济有效的提供心理社会治疗的方法。
