对白细胞介素 9 的肠道反应。
A gut reaction to IL-9.
机构信息
Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
出版信息
Nat Immunol. 2014 Jul;15(7):599-600. doi: 10.1038/ni.2916.
Abstract
The pathogenesis of inflammatory bowel disease is orchestrated by specific subsets of cytokine-secreting T cells. The interleukin 9–producing subset of helper T cells contributes to the pathogenesis of inflammatory bowel disease in part by disrupting intestinal barrier function and impairing tissue-repair mechanisms.
摘要
炎症性肠病的发病机制是由特定亚群的细胞因子分泌 T 细胞协调的。辅助性 T 细胞产生的白细胞介素 9 亚群通过破坏肠道屏障功能和损害组织修复机制，在一定程度上促进了炎症性肠病的发病机制。
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