Stock Eileen M, Kimbrel Nathan A, Meyer Eric C, Copeland Laurel A, Monte Ralph, Zeber John E, Gulliver Suzy Bird, Morissette Sandra B
Center for Applied Health Research, Central Texas Veterans Health Care System in collaboration with Scott & White Healthcare, Temple, TX, USA; Texas A&M Health Science Center, College of Medicine, Bryan, TX, USA.
Int J Methods Psychiatr Res. 2014 Sep;23(3):345-58. doi: 10.1002/mpr.1442. Epub 2014 Jun 18.
Many Veterans from the conflicts in Iraq and Afghanistan return home with physical and psychological impairments that impact their ability to enjoy normal life activities and diminish their quality of life (QoL). The present research aimed to identify predictors of QoL over an eight-month period using Bayesian model averaging (BMA), which is a statistical technique useful for maximizing power with smaller sample sizes. A sample of 117 Iraq and Afghanistan Veterans receiving care in a southwestern health care system was recruited, and BMA examined the impact of key demographics (e.g., age, gender), diagnoses (e.g., depression), and treatment modalities (e.g., individual therapy, medication) on QoL over time. Multiple imputation based on Gibbs sampling was employed for incomplete data (6.4% missingness). Average follow-up QoL scores were significantly lower than at baseline (73.2 initial versus 69.5 four-month and 68.3 eight-month). Employment was associated with increased QoL during each follow-up, while post-traumatic stress disorder and Black race were inversely related. Additionally, predictive models indicated that depression, income, treatment for a medical condition, and group psychotherapy were strong negative predictors of four-month QoL but not eight-month QoL.
许多来自伊拉克和阿富汗冲突地区的退伍军人回国时伴有身体和心理损伤,这些损伤影响了他们享受正常生活活动的能力,并降低了他们的生活质量(QoL)。本研究旨在使用贝叶斯模型平均法(BMA)确定八个月期间生活质量的预测因素,BMA是一种有助于在较小样本量下最大化功效的统计技术。招募了117名在西南医疗系统接受治疗的伊拉克和阿富汗退伍军人作为样本,BMA研究了关键人口统计学特征(如年龄、性别)、诊断结果(如抑郁症)和治疗方式(如个体治疗、药物治疗)随时间对生活质量的影响。对于不完整数据(缺失率为6.4%),采用基于吉布斯抽样的多重插补法。平均随访生活质量得分显著低于基线水平(初始时为73.2,四个月时为69.5,八个月时为68.3)。在每次随访期间,就业与生活质量提高相关,而创伤后应激障碍和黑人种族则呈负相关。此外,预测模型表明,抑郁症、收入、医疗状况治疗和团体心理治疗是四个月生活质量的强负预测因素,但不是八个月生活质量的强负预测因素。