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[肿瘤疾病中的血清半乳糖基转移酶]

[Blood serum galactosyltransferase in oncologic diseases].

作者信息

Mikhaĭlov A D, Zhordaniia K I, Ivanov P K

出版信息

Med Radiol (Mosk). 1989 Mar;34(3):31-4.

PMID:2494414
Abstract

The paper is concerned with comparative analysis of the results of the determination of activity of galactosyl transferase, CEA and antigen CA-125 in the blood serum of 44 healthy persons, 70 cancer patients and 12 patients with benign diseases. It was shown that a radiometric test for galactosyl transferase in its diagnostic sensitivity was not inferior to CEA in stomach and ovarian tumors and exceeded the test for antigen CA-125 in ovarian cancer. In colon cancer the diagnostic accuracy of the tests for the activity of galactosyl transferase and CEA turned out to be identical. The most reliable diagnostic test in acute lymphoblastic leukemia in children was the test for galactosyl transferase activity.

摘要

本文对44名健康人、70名癌症患者和12名良性疾病患者血清中半乳糖基转移酶、癌胚抗原(CEA)和抗原CA - 125的活性测定结果进行了比较分析。结果表明,半乳糖基转移酶的放射测定法在诊断敏感性方面,对于胃癌和卵巢癌并不亚于癌胚抗原,且在卵巢癌中超过了抗原CA - 125检测。在结肠癌中,半乳糖基转移酶活性检测和癌胚抗原检测的诊断准确性相同。儿童急性淋巴细胞白血病中最可靠的诊断检测是半乳糖基转移酶活性检测。

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