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胸骨柄受限胸骨切开术可减少主动脉瓣置换术后的失血量。

Manubrium-limited sternotomy decreases blood loss after aortic valve replacement surgery.

作者信息

Burdett Clare L, Lage Ignacio Bibiloni, Goodwin Andrew T, White Ralph W, Khan Khalid J, Owens W Andrew, Kendall Simon W H, Ferguson Jonathan I, Dunning Joel, Akowuah Enoch F

机构信息

Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough UK.

Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough UK

出版信息

Interact Cardiovasc Thorac Surg. 2014 Oct;19(4):605-10. doi: 10.1093/icvts/ivu196. Epub 2014 Jun 18.

Abstract

OBJECTIVES

Minimally invasive surgical approaches for aortic valve replacement (AVR) are growing in popularity in an attempt to decrease morbidity from conventional surgery. We have adopted a technique that divides only the manubrium and spares the body of the sternum. We sought to determine whether patients benefit from this less-invasive approach.

METHODS

We retrospectively analysed our prospectively maintained database to review all isolated aortic valve replacements performed in an 18-month period from November 2011 to April 2013.

RESULTS

One hundred and ninety-one patients were identified, 98 underwent manubrium-limited sternotomy (Mini-AVR) and 93 had a conventional median sternotomy (AVR). The two groups were well matched for preoperative variables and risk (mean logistic EuroSCORE mini-AVR 7.15 vs AVR 6.55, P = 0.47). Mean cardiopulmonary bypass and aortic cross-clamp times were 10 and 6 min longer, respectively, in the mini-AVR group (mean values 88 vs 78 min, P = 0.00040, and 66 vs 60 min, P = 0.0078, respectively). Mini-AVR patients had significantly less postoperative blood loss, 332 vs 513 ml, P = 0.00021, and were less likely to require blood products (fresh-frozen plasma and platelets), 24 vs 36%, P = 0.042. Postoperative complications and length of stay were similar (discharge on or before Day 4; mini-AVR 15 vs AVR 8%, P = 0.17). Valve outcome (paravalvular leak mini-AVR 2 vs AVR 1%, P = 1.00) and survival (mini-AVR 99 vs AVR 97%, P = 0.36) were equal.

CONCLUSIONS

A manubrium-limited approach maintains outcomes achieved for aortic valve replacement by conventional sternotomy while significantly reducing postoperative blood loss and transfusion of blood products.

摘要

目的

主动脉瓣置换术(AVR)的微创手术方法越来越受欢迎,旨在降低传统手术的发病率。我们采用了一种仅切开胸骨柄而保留胸骨体的技术。我们试图确定患者是否能从这种侵入性较小的方法中获益。

方法

我们回顾性分析了前瞻性维护的数据库,以回顾2011年11月至2013年4月这18个月期间进行的所有单纯主动脉瓣置换术。

结果

共确定191例患者,98例行胸骨柄有限切开术(Mini-AVR),93例行传统正中胸骨切开术(AVR)。两组术前变量和风险匹配良好(平均逻辑EuroSCORE Mini-AVR为7.15,AVR为6.55,P = 0.47)。Mini-AVR组的平均体外循环和主动脉阻断时间分别长10分钟和6分钟(平均值分别为88分钟对78分钟,P = 0.00040;66分钟对60分钟,P = 0.0078)。Mini-AVR患者术后失血量明显较少,分别为332 ml对513 ml,P = 0.00021,且需要血液制品(新鲜冰冻血浆和血小板)的可能性较小,分别为24%对36%,P = 0.042。术后并发症和住院时间相似(第4天或之前出院;Mini-AVR为15%,AVR为8%,P = 0.17)。瓣膜结局(瓣周漏Mini-AVR为2%,AVR为1%,P = 1.00)和生存率(Mini-AVR为99%,AVR为97%,P = 0.36)相当。

结论

胸骨柄有限切开术在维持传统胸骨切开术进行主动脉瓣置换术所取得的疗效的同时,显著减少了术后失血量和血液制品的输注。

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