Li Wei, Xue Qian, Liu Kai, Hong Jiang, Xu Jibin, Wu Lihui, Ji Guangyu, Wang Zhinong, Zhang Yufeng
Department of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China (mainland).
Med Sci Monit. 2016 Apr 2;22:1085-92. doi: 10.12659/msm.896558.
The effects of minimally invasive aortic valve surgery (MIAVS) on the early postoperative extravascular lung water index (ELWI) and respiratory mechanics have rarely been studied.
MATERIAL/METHODS: A total of 90 patients were divided into 3 groups: a conventional full sternotomy (CS) group (n=30), an upper ministernotomy (US) group (n=30), and a right anterior thoracotomy (RT) group (n=30). Hemodynamic and respiratory mechanics parameters were recorded at perioperative time points, including before skin incision (T(-1)); at sternum closing (T0); and 4 h (T4), 8 h (T8), 12 h (T12), and 24 h (T24) after the operation. The ventilator support time, ICU length of stay, and postoperative hospitalization time, as well as the thoracic drainage volume and blood transfusion volume, were recorded.
The ELWI and pulmonary vascular permeability index (PVPI) increased at T4, and the values were significantly lower in the US group than in the RT group and CS group (P<0.05). At T8, the ELWI and PVPI in the US group and RT group were significantly lower than in the CS group. At T12, there were no significant differences among the 3 groups. In addition, at T4 static lung compliance decreased, plateau airway pressure increased, and airway resistance changed non-significantly. There were no significant differences between the US group and the RT group, but both groups showed better results than the CS group did.
The ELWI and PVPI may transiently increase after aortic valve surgery with cardiopulmonary bypass. Compared with the 12 h required to recover from a conventional sternotomy operation, it may only take 8 h to recover from MIAVS.
微创主动脉瓣手术(MIAVS)对术后早期血管外肺水指数(ELWI)及呼吸力学的影响鲜有研究。
材料/方法:90例患者分为3组:传统正中开胸(CS)组(n = 30)、上半胸骨切开(US)组(n = 30)和右前外侧开胸(RT)组(n = 30)。记录围手术期各时间点的血流动力学和呼吸力学参数,包括皮肤切开前(T(-1))、胸骨关闭时(T0)、术后4小时(T4)、8小时(T8)、12小时(T12)和24小时(T24)。记录呼吸机支持时间、重症监护病房(ICU)住院时间、术后住院时间以及胸腔引流量和输血量。
T4时ELWI和肺血管通透性指数(PVPI)升高,US组的值显著低于RT组和CS组(P < 0.05)。T8时,US组和RT组的ELWI和PVPI显著低于CS组。T12时,3组间无显著差异。此外,T4时静态肺顺应性降低,平台气道压升高,气道阻力变化不显著。US组和RT组之间无显著差异,但两组均比CS组效果更好。
体外循环下主动脉瓣手术后ELWI和PVPI可能会短暂升高。与传统胸骨切开手术恢复所需的12小时相比,MIAVS恢复可能仅需8小时。